“Chemoenzymatic cascades of new Cu and Pd reactions of significant application potential”
Currently, an increase in the incidence of cancer is observed, thus it is extremely important to eliminate or limit them. One of types of cancer is multidrug resistant (MDR) solid tumors.. The key challenge of this action is an identification of a new diagnostic/predictive biomarkers, producing new and safe compounds applicable to personalized treatments of MDR tumors. In order to achieve such goal, we need to design new synthetic protocols providing organic compounds of defined structure, free from any impurities. Therefore, during the realization of project we will study a new type of organic reactions catalyzed by copper salts, which provide molecules of high activity towards MDR. To achieve success, we need to know reaction scope and limitations, reaction mechanisms and optimal conditions for successful synthesis. Since the obtained products will be applied for biological and medical studies by COST specialists, they should be free from impurities including residual metal catalyst. Therefore, in the project special attention will be paid on reaction conditions and catalyst immobilization/inclusion to design experimental procedure providing metal free products.
Description of tasks: Analysis of data collected in our team and analysis of literature data. Synthesis of catalysts. Performing catalytic reactions with copper-based catalysts and discovery new catalytic reactions based on data analysis. Preparation of reports and manuscripts.
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1
Terms of employment: stipend (including employer’s costs) 5000 PLN per month (~4200 PLN gross), scholarship paid from grant for 12 months with possible extension.
Benefits: participation in EU COST projects, private medical care package, access to the dormitory for PhD students
Career development opportunities: work in dynamic team, access to research infrastructure, professional development in the field of asymmetric synthesis, the possibility of cooperation with foreign research centers, the possibility of further professional development at the IOC PAS
Project manager: prof. Ryszard Ostaszewski
Phone: +48 22 3432054
e-mail: ryszard.ostaszewski@icho.edu.pl
A prerequisite for qualifying for the project is the PhD student status at the Warsaw PhD School in Natural and BioMedical Sciences (the interviews will be held from 26 June 2023 to 5 July 2023; the deadline for submitting documents to the doctoral school is June 4th, 2023), details are available on the Warsaw4PhD School website as well as the Institute of Organic Chemistry PAS website.
Required competences
Desirable competences
Along with the required documents, please submit (or send a scan) a signed consent to the processing of personal data available at: https://www.icho.edu.pl/en/cooperations/career/
12.06.2023 23:59
10.07.2023
Envisaged job starting date: 01.10.2023
Secretariat
Institute of Organic Chemistry of the Polish Academy of Sciences
Kasprzaka 44/52 Street
01-224 Warsaw
Phone: +48 22 631 8788
e-mail: rekrutacja@icho.edu.pl
ATTENTION! In the title of the e-mail, please enter “Recruitment – Ryszard Ostaszewski”
“Palladium-catalyzed cascades for the rapid and enantioselective construction of polycyclic scaffolds of alkaloids and pseudo-natural products”
The aim of the project is the development of palladium-catalyzed cascade reactions forming polycyclic nitrogen-containing structures, corresponding to the skeletons of natural alkaloids and their analogues. An important goal is to design and optimize these catalytic reactions also in enantioselective manner by performing them in the presence of chiral ligands. The work will involve multi-step syntheses of the precursors for the Pd-catalyzed cascade reactions, optimization of the cascade reactions, spectroscopic and HPLC analysis of the products, preparation of the results for publication.
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2
Terms of employment: scholarship for 48 months – stipend (including employer’s costs) 5,000 PLN per month (~4,200 PLN gross) paid from NSC grant
Type of contract: temporary
Job status: full time
Hours per week: 40
Benefits: medical care package, co-financing of sports cards, possibility of accommodation at the Doctoral Hotel
Career development opportunities: professional development in the field of organic synthesis and analysis of organic compounds, access to research infrastructure, the possibility of further professional development at the IOC PAS)
Project manager: Assoc. Professor Rafał Loska
Phone: +48 22 343 2108, +48 602 855 591
e-mail: rafal.loska@icho.edu.pl
www.icho.edu.pl/zespol/rafal-loska
A prerequisite for qualifying for the project is the PhD student status at the Warsaw PhD School in Natural and BioMedical Sciences (the interviews will be held from 26 June 2023 to 5 July 2023; the deadline for submitting documents to the doctoral school is June 4th, 2023), details are available on the Warsaw4PhD School website as well as the Institute of Organic Chemistry PAS website.
Required competencies
Desirable competences
Along with the required documents, please submit (or send a scan) a signed consent to the processing of personal data available at: https://www.icho.edu.pl/en/cooperations/career/
2023-06-20 12:00
17.07.2023
Envisaged job starting date: 01.10.2023
Secretariat
Institute of Organic Chemistry of the Polish Academy of Sciences
Kasprzaka 44/52 Street
01-224 Warsaw
Phone: +48 22 631 8788
e-mail: rekrutacja@icho.edu.pl
ATTENTION! In the title of the e-mail, please enter “Recruitment – Rafał Loska”
“Chasing lithium: direct lithium salt extraction and purification from mixtures using stimuli-responsive “smart” molecular extractants”
Motivation: The rapid development of the electrotechnical industry has contributed to a dramatic growth in demand for lithium, which is used primarily in Li-ion batteries. This element is crucial for shifting our society from burning fossil fuels to clean energy generated from renewable sources. Considering the strategic interest in this most valuable resource of the 21st century, identifying and developing the practical and most sustainable lithium supply and recycling strategy is crucial for a successful transition to a low-carbon economy. Lithium is extracted primarily from minerals and brines and, to a lesser extent, from spent Li-ion batteries. In these resources, lithium typically co-occurs with various metal salts (e.g., sodium, potassium, magnesium, and calcium). The similarity between the associated salts (e.g., NaCl vs. LiCl) renders selective extraction of lithium a challenging and resource-consuming task. In addition, alternative potentially competing metal cations, such as magnesium and calcium, featuring higher specific charge densities often make selective lithium binding even more challenging. However, the current methods have significant limitations, such as tremendous energy requirements or the need to use large amounts of water and toxic reactants, resulting in a massive environmental impact. Thus, developing sustainable lithium extraction and purification technologies is one of the key research directions. Studies toward using synthetic molecular receptors containing cation and anion binding sites in their structure is an appealing solution to achieve direct lithium extraction (DLE) from the mixtures. However, the current molecular extractants have some limitations, such as inefficient synthesis, poor lithium selectivity, and slow kinetics of lithium salt release due to the high stability of the formed complex. In other words, lithium extraction using these systems can take from hours to days. Consequently, these systems are not suitable for practical use.
The aim of the research: In this project, we will evaluate the feasibility of employing photoswitchable receptors as direct extractants and transporters of lithium salts (Li-salts) of industrial importance, such as lithium chloride (LiCl). In principle, these “smart” systems exhibit capability for directly extracting Li-salts from the mixtures of various competing solid salts and their aqueous solutions to organic solvents, from which Li-salt can be recovered in pure form. The proposed azobenzene-based electroneutral extractants are equipped with lithium-cation-selective binding groups and anion binding groups selected for particular anions such as chloride.
We expect that the native trans-form of the extractant will demonstrate a weak affinity for Li-salts due to the spatial separation of cation and anion binding domains. In contrast, the light-generated metastable cis-form of the extractant will show superior binding, extraction, and transport of Li-salt due to the proximity and advantageous arrangement of ion-binding domains, shielding the guest from the environment. The efficient bidirectional trans/cis isomerization of the robust azobenzene linker allows control of the complex’s thermodynamic stability and the rate of catching and releasing Li-salt from the host binding cavity. All these features will enable efficient and energy-efficient management of the Li-salt binding and release process, allowing the development of the continuous extraction of Li-salt from the mixtures for the first time.
The project is divided into sections. Firstly, we will initiate the theoretical studies to predict the molecular properties of the proposed trans/cis-extractants and their putative complexes with various salts, such as chlorides of alkali metal cations. We aim to synthesize only the compounds predicted to display selectivity for lithium over competing cations. Then, for chosen systems, we will examine in detail their solution-binding properties and extraction efficiency with more time-consuming 1H/7Li NMR titration techniques and solid-liquid- (SLE) and liquid-liquid extraction (LLE) studies. The theoretical model will be tuned due the course of the project by comparison with the experimental data from the binding and extraction studies. Finally, selected hosts will be tested continuously as the first stimuli-responsive lithium salt extractants using a custom-made testing apparatus.
Description of tasks:
The key responsibilities of the Ph.D. student include the following:
R1
1
Terms of employment: scholarship for 48 months: stipend (including employer’s costs) 5,000 PLN per month (~4200 PLN gross) for 48 months.
Type of contract: temporary,
Job status: full time
Hours per week: 40
Benefits: Private medical care package, co-financing of sports cards, possibility of accommodation at the Doctoral Hotel
Career development opportunities: Possibility of working in a young, dynamic team with access to top research infrastructure. During the project, the prospective PhD student will acquire skills and experience in chemical robotics, which are essential in the pharmaceutical and chemical industries. As well as the opportunity for further professional development at the IOC PAS.
Project manager: Dr Kajetan Dąbrowa
Phone: +48 22 343 2127; +48 509 294 060
e-mail: kajetan.dabrowa@icho.edu.pl
A prerequisite for qualifying for the project is the PhD student status at the Warsaw PhD School in Natural and BioMedical Sciences (the interviews will be held from June 26 to July 05, 2023; the deadline for submitting documents to the doctoral school is June 04, 2023), details are available on the Warsaw4PhD School website Doctoral website as well as the Institute of Organic Chemistry PAS website.
Required competencies
Desirable competences
Along with the required documents, please submit (or send a scan) a signed consent to the processing of personal data available at: https://www.icho.edu.pl/en/cooperations/career/
20.06.2023 23:59
10.07.2023
Envisaged job starting date: 01.10.2023
Secretariat
Institute of Organic Chemistry of the Polish Academy of Sciences
Kasprzaka 44/52 Street
01-224 Warsaw
Phone: +48 22 631 8788
e-mail: rekrutacja@icho.edu.pl
ATTENTION! In the title of the e-mail, please enter “Recruitment – Kajetan Dąbrowa”
Candidates who are not PhD Students of the Doctoral School must take part in the recruitment process to the Warsaw-4-PhD Doctoral School! Details available here!
“Dual Catalytic System Based on Combination of MHAT and SH2 Mechanisms: A Novel Platform for Formal Cross-Coupling of Transient Radicals”
The main tasks will involve:
– design and synthesis of base-metal-complexes
– investigation of new catalytic radical reactions including photo- or electrochemistry
– mechanistic investigations
– scope and limitation studies
– data analysis using state-of-the-art techniques (e.g. NMR, GCMS, CV)
– preparation of reports and publication manuscripts
R1
1
Benefits:
Career development opportunities:
Project manager: dr Michał Ociepa
Phone: +48 667-786-464 (WhatsApp only)
e-mail: michal.ociepa@icho.edu.pl (preferred)
A prerequisite for qualifying for the project is the PhD student status at the Warsaw PhD School in Natural and BioMedical Sciences (the interviews will be held from 26 June 2023 to 5 July 2023; the deadline for submitting documents to the doctoral school is June 4th, 2023), details are available on the Warsaw4PhD School website as well as the Institute of Organic Chemistry PAS website.
Required competencies
– Master’s degree or equivalence in chemistry (awarded before 01.10.2023)
– strong organic chemistry knowledge
– previous experience with synthetic chemistry laboratory techniques
– communicate well in English in writing and in oral presentation, be able to write
reports in English
– high self-motivation
– ability to plan and perform work independently and as a part of a team
Desirable competences
– previous experience in organic synthesis and catalysis
– strong work ethic
– creativity
Along with the required documents, please submit (or send a scan) a signed consent to the processing of personal data available at: https://www.icho.edu.pl/en/cooperations/career/
2023-06-12 23:59
2023-07-10
Envisaged job starting date: 01.10.2023
Secretariat
Institute of Organic Chemistry of the Polish Academy of Sciences
Kasprzaka 44/52 Street
01-224 Warsaw
Phone: +48 22 631 8788
e-mail: rekrutacja@icho.edu.pl
ATTENTION! In the title of the e-mail, please enter “Recruitment – Michal Ociepa
Candidates who are not PhD Students of the Doctoral School must take part in the recruitment process to the Warsaw-4-PhD Doctoral School! Details available here!
“Donor-acceptor-doped acenes and cyclacenes”
Key responsibilities include the synthesis of acene and cyclacene analogues doped with donor and acceptor heteroatoms, in particular: synthesis of building blocks and precursors, purification of products, complete chemical, spectral, and photophysical characterization of the obtained products, documentation of the experiments, and participation in the preparation of scientific publications.
R1
1
Benefits: Private medical care package, co-financing of sports cards, possibility of accommodation at the Doctoral Hotel.
Career development opportunities: Access to advanced research infrastructure, professional development in the field of organic synthesis, the possibility of cooperation with foreign research centres, participation in international conferences.
Project manager: Marek Grzybowski
e-mail: marek.grzybowski@icho.edu.pl
Admission to doctoral studies at Warsaw PhD School in Natural and BioMedical Sciences (Warsaw-4-PhD). The deadline for submitting documents to the doctoral school is June 4, 2023, details are available on the website icho.edu.pl and https://warsaw4phd.eu/
Required competencies
Desirable competences
Required research experience:
Research field: Chemistry
Years of research experience: 1-4
Required Languages:
Language: English
Level: Good
Required Education Level:
Main research field: Chemistry
Level: Master degree
Along with the required documents, please submit (or send a scan) a signed consent to the processing of personal data available at: https://www.icho.edu.pl/en/cooperations/career/
2023-06-10 16:00
2023-07-17
Envisaged job starting date: 2023.10.01
Secretariat
Institute of Organic Chemistry of the Polish Academy of Sciences
Kasprzaka 44/52 Street
01-224 Warsaw
Phone: +48 22 631 8788
e-mail: rekrutacja@icho.edu.pl
ATTENTION! In the title of the e-mail, please enter “Recruitment – Marek Grzybowski”
Candidates who are not PhD Students of the Doctoral School must take part in the recruitment process to the Warsaw-4-PhD Doctoral School! Details available here!
“Stereoselective dearomatization of nonactivated arenes via an „alkene walk” pathway: Rapid access to high-added value poly- and spirocyclic systems from readily available aromatic compounds”
The aim of this research proposal is to establish a new methodology for the stereoselective dearomatization of nonactivated arenes via the virtually unexplored retro-ene reaction of in situ generated benzylic diazenes (a so called “alkene walk” process), and subsequent transformation of the so formed active polyene species into chiral poly- and spirocyclic molecules. As a result, a new and versatile tool for the synthesis of high-value organic molecules from cheap and readily available benzylic alcohols, halides, aldehydes (in combination with organometallics) and monosilyl diazenes will be added to the organic chemist’s toolbox. Moreover, the possibility of synthesis of advanced polyaromatic systems via an additional re-aromatization process will be tested.
Stereoselective dearomatizations, especially in non-activated arenes, allowing conversion of readily available planar aromatic compounds into three-dimensionally complex molecules with precise control of reaction site, regio- and stereoselectivity has long been an exciting challenge in organic synthesis. Due to their high resonance stabilization energy, dearomatizations of nonactivated arenes usually require the use of stoichiometric amounts of expensive and toxic transition metal activators or elevated temperatures and harsh reaction conditions. This makes achieving high stereoselectivity in these processes very difficult. In our approach aromatic substrates are initially transformed into highly active polyenes which can then further derivatized using the broad spectrum of well-established stereoselective reactions of alkenes and dienes conducted under mild reaction conditions, resulting in highly stereoselective dearomatizations. Further advantages of the method include high availability of substrates (in the case of chiral derivatives in both enantiomeric forms in high optical purity) and high chemo- and stereodiversity of the obtained products.
The candidate will be responsible for synthesizing of the starting materials and polyene intermediates, followed by an studies on their selective of transformations into variety of poly- and spirocyclic systems using selected literature protocols. The candidate will also be responsible for recording and interpreting spectral data, designing experiments, and preparing reports and materials for publications. Complementary theoretical studies on reaction mechanisms may be performed by the candidate or as part of a collaboration, depending on the scholar’s interests.
The PhD candidate will also participate in the Institute scientific life by attending to group and institute seminars and lectures. The PhD candidate will also attend to advanced course devoted to modern organic chemistry and spectroscopy.
R1
1
Terms of employment: scholarship for 48 months – stipend (including employer’s costs) 5,000 PLN per month (~4200 PLN gross) paid from NSC grant
Benefits: private medical care package, co-financing of sports cards, possibility of accommodation at the Doctoral Hotel
Career development opportunities:
Project manager: dr hab. Bartosz Zambroń
Phone: +48 22 343 2141
e-mail: bartosz.zambron@icho.edu.pl
A prerequisite for qualifying for the project is the PhD student status at the Warsaw PhD School in Natural and BioMedical Sciences (the interviews will be held from 26 June 2023 to 5 July 2023; the deadline for submitting documents to the doctoral school is June 4th, 2023), details are available on the Warsaw4PhD School website as well as the Institute of Organic Chemistry PAS website.
Required competencies
Desirable competences
Along with the required documents, please submit a signed consent to the processing of personal data available at: https://www.icho.edu.pl/en/cooperations/career/
2023-06-04 23:59
2023-07-16
Envisaged job starting date: 1.10.2023
Secretariat
Institute of Organic Chemistry of the Polish Academy of Sciences
Kasprzaka 44/52 Street
01-224 Warsaw
Phone: +48 22 631 8788
e-mail: rekrutacja@icho.edu.pl
ATTENTION! In the title of the e-mail, please enter “Recruitment – Bartosz Zambron”
Candidates who are not PhD Students of the Doctoral School must take part in the recruitment process to the Warsaw-4-PhD Doctoral School! Details available here!
“Novel tricyclic glycomimetics as DC-SIGN receptor ligands”
Synthesis and characterization of organic compounds as well as investigation of ligand-receptor binding properties using nuclear magnetic resonance (NMR) and isothermal titration calorimetry (ITC) methods. The work will be carried out in close collaboration with other PhD students, post-docs, and other co-investigators from IOC PAS and collaborative Polish and foreign institutions.
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2
Benefits: private medical care package, co-financing of sports cards, and the possibility of accommodation at the Doctoral Hotel.
Career development opportunities: work in a young, dynamically developing team, access to the research infrastructure of IOC PAS, professional development in the field of organic and medicinal chemistry, the possibility of cooperation with foreign research centers, the possibility of further professional development at the IOC PAS.
Project manager: Mykhaylo Potopnyk, DSc
Phone: +4822 3432132
e-mail: mykhaylo.potopnyk@icho.edu.pl
A prerequisite for qualifying for the project is the PhD student status at the Warsaw PhD School in Natural and BioMedical Sciences (the interviews will be held from 26 June 2023 to 5 July 2023; the deadline for submitting documents to the doctoral school is June 4th, 2023), details are available on the Warsaw4PhD School website as well as the Institute of Organic Chemistry PAS website.
Required competencies
Desirable competences
Candidate’s Curriculum Vitae
Along with the required documents, please submit (or send a scan) a signed consent to the processing of personal data available at: https://www.icho.edu.pl/en/cooperations/career/
2023-06-04 12:59
2023-07-16
Envisaged job starting date: 01.10.2023
Secretariat
Institute of Organic Chemistry of the Polish Academy of Sciences
Kasprzaka 44/52 Street
01-224 Warsaw
Phone: +48 22 631 8788
e-mail: rekrutacja@icho.edu.pl
ATTENTION! In the title of the e-mail, please enter “Recruitment – Mykhaylo Potopnyk”
Candidates who are not PhD Students of the Doctoral School must take part in the recruitment process to the Warsaw-4-PhD Doctoral School! Details available here!
“M-ERA.NET 3, 2022/04/Y/ST4/00152; Steep absorption with supramolecular self-assembled functional dyes for vacuum-deposited organic solar cells (“STEEP UP”)”
The scope of duties includes analysis of the literature on new organic semiconductors and transformations enabling the implementation of the proposed synthetic pathways, optimization and carrying out of organic syntheses on a laboratory and preparative scale, purification and isolation of compounds intermediates by means of precipitation, maceration, crystallization, column chromatography. Identification of obtained compounds by using spectroscopic tools and critical analysis of obtained results, their presentation (team seminars) and written two-weeks reports.
Recognised Researcher (R2)/Established Researcher (R3)
1
Type of contract: temporary, 36 months
Job status: full time,
Hours per week: 40
Salary: (including employer’s costs) 11,666 PLN per month (~ 9 700 PLN gross)
Benefits: private medical care package, co-financing of sports cards;
Career development opportunities:
Project manager: Dr. Mariusz Tasior
Phone: +48 22 343 2036
e-mail: mariusz.tasior@icho.edu.pl
Required competencies
Desirable competences
Along with the required documents, please submit (or send a scan) a signed consent to the processing of personal data available at: https://www.icho.edu.pl/en/cooperations/career/
2023-05-22 14:00
2023-05-31
Envisaged job starting date: 01.06.2023
Secretariat
Institute of Organic Chemistry of the Polish Academy of Sciences
Kasprzaka 44/52 Street
01-224 Warsaw
Phone: +48 22 631 8788
e-mail: rekrutacja@icho.edu.pl
ATTENTION! In the title of the e-mail, please enter “Recruitment – Mariusz Tasior”
“Artificial intelligence-driven design and discovery of chiral phosphoric acid catalysed reactions”
Assymetric synthesis is one of the most important branches of contemporary organic chemistry as synthesis of chiral compounds is of great interest in the fields of materials science, agrochemicals and pharmaceutical industry. However, the discovery of novel asymmetric transformations is usually time-consuming and relies in many cases on serendipity. The artificial methods promise to speed up the navigation of chemical space, but little is known how to design new transformations from first principles. Deep learning was successfully applied to many fields achieving super-human performance, yet its full potential in chemistry is to be achieved. The current project investigates the application of machine learning methods and the successful candidate will be involved in discovery and optimization of new catalytic reactions. The work will include organic synthesis of starting materials and reagents, as well as substrate scope investigation, products structure determination, formulation of research hypotheses, analysis and interpretation of obtained results.
R2
1
Terms of employment: full time, temporary contract for 12 months with the possibility to be extended up to 24 months total, hours per week: 40; salary (including employer’s costs) 10,000 PLN per month (~ 8 300 PLN gross);
Benefits: Private medical care package, co-financing of sports cards;
Career development opportunities: Work in a young, dynamic team, access to research infrastructure. As well as the opportunity for further professional development at the IOC PAS.
Project manager: Dr Jaroslaw Granda
Phone: +48 22 343 2021; +48 697 231 776
e-mail: jaroslaw.granda@icho.edu.pl
required competences
desirable competences
Along with the required documents, please submit (or send a scan) a signed consent to the processing of personal data available at: https://www.icho.edu.pl/en/cooperations/career/
2023-04-30 23:59
2023-05-16
Envisaged job starting date: 01.06.2023
Secretariat
Institute of Organic Chemistry of the Polish Academy of Sciences
Kasprzaka 44/52 Street
01-224 Warsaw
Phone: +48 22 631 8788
e-mail: rekrutacja@icho.edu.pl
ATTENTION! In the title of the e-mail, please enter “Recruitment – Jaroslaw Granda”
“Ambipolar, bowl-shaped polyaromatic compounds with manifold, precisely arranged, nitrogen dopants. Unprecedented class of efficient OLED emitters (BOwLEDs).”
The scope of duties includes analysis of the literature on non-planar organic compounds, TADF active materials, the chemistry of PAHs, aromatic compounds and transformations enabling the implementation of the proposed synthetic pathways, optimization and carrying out of organic syntheses on a laboratory and preparative scale, purification and isolation of compounds intermediates by means of precipitation, maceration, crystallization, column chromatography. Identification of obtained compounds by using spectroscopic tools and critical analysis of obtained results, their presentation (team seminars) and written two-weeks reports. Postdoc will visit a laboratory of Prof. Przemysław Data to get practical knowledge regarding OLEDs fabrication and their analysis.
R2/R3
1
Type of contract: temporary, 8 months with the possibility to be extended up to 40 months total
Job status: full time,
Hours per week: 40
Benefits: private medical care package
Career development opportunities:
Project manager: Marcin Lindner
Phone: +48 22 343 2031
e-mail: marcin.lindner@icho.edu.pl
required competencies
desirable competences
Along with the required documents, please submit (or send a scan) a signed consent to the processing of personal data available at: https://www.icho.edu.pl/en/cooperations/career/
2023-03-29 14:00
2023-03-31
Envisaged job starting date: 01.04.2023
Secretariat
Institute of Organic Chemistry of the Polish Academy of Sciences
Kasprzaka 44/52 Street
01-224 Warsaw
Phone: +48 22 631 8788
e-mail: rekrutacja@icho.edu.pl
ATTENTION! In the title of the e-mail, please enter “Recruitment – Marcin Lindner”
“RED LIGHT – A TOOL FOR ORGANIC AND BIOORTHOGONAL CHEMISTRY”
Description of tasks:
R2/R3
1
Terms of employment: full time, temporary, 12 months with the possibility to be extended up to 36 months total, gross salary (including employer’s costs)
10,000 PLN per month (~ 8 300 PLN gross);
Benefits: private medical care package
Career development opportunities:
Project manager: prof. Dorota Gryko
Phone: +48 22 343 20 51
e-mail: dorota.gryko@icho.edu.pl
required competences
desirable competences
Along with the required documents, please submit (or send a scan) a signed consent to the processing of personal data available below.
2023-03-23 23:59
2023-04-14
Envisaged job starting date: 01.05.2023
Applications should be sent by e-mail.
Secretariat
Institute of Organic Chemistry of the Polish Academy of Sciences
Kasprzaka 44/52 Street
01-224 Warsaw
Phone: +48 22 631 8788
e-mail: rekrutacja@icho.edu.pl
ATTENTION! In the title of the e-mail, please enter “Recruitment – Dorota Gryko”
“Degradation of hazardous chemical compounds into valuable building blocks: from computer-planned routes to experimental validation”
This project aims to address one important aspect of sustainable chemistry, namely, discovery of novel methodologies to convert hazardous or unwanted chemical waste into useful products. We will provide new strategies leading to valuable building blocks based on degradation protocols. Such multistep chemical and chemo-enzymatic pathways designed by the computer will be selected and executed in the laboratory.
Description of tasks:Person employed in this position will be responsible for performing computational calculations, verification that pathways are novel (comparison with databases of published reactions), planning experiments, cultivation and harvesting of microorganisms relevant to biocatalytic steps, performing chemical and mirobiological experiments in the chemical laboratory, analysis and identification of chemical compounds, analysis of obtained results, participation in the writing of manuscripts, presentation of project results.
R2
1
Project manager: dr Anna Żądło-Dobrowolska
Phone: +48 22 343 21 17
e-mail: azadlo@icho.edu.pl
Along with the required documents, please send a scan of a signed consent to the processing of personal data available below.
Candidates will be evaluated on the basis of submitted applications.
2022-12-28 15:00
2022-12-29
Envisaged job starting date: 30.12.2022 r.
Please send your applications to e-mail: rekrutacja@icho.edu.pl
Secretariat
Institute of Organic Chemistry of the Polish Academy of Sciences
Kasprzaka 44/52 Street
01-224 Warsaw
Phone: +48 22 631 8788
ATTENTION! In the title of the e-mail, please enter “Recruitment – Anna Zadlo-Dobrowolska“
“Chemoenzymatic cascades of new Cu and Pd reactions of significant application potential”
Currently, an increase in the incidence of cancer is observed, thus it is extremely important to eliminate or limit them. One of types of cancer is multidrug resistant (MDR) solid tumors. This is the subject of COST action CA17104. The key challenge of this action is an identification of a new diagnostic/predictive biomarkers, producing new and safe compounds applicable to personalized treatments of MDR tumors. In order to achieve such goal, we need to design new synthetic protocols providing organic compounds of defined structure, free from any impurities. Therefore, during the realization of project we will study a new type of organic reactions catalyzed by copper salts, which provide molecules of high activity towards MDR. To achieve success, we need to know reaction scope and limitations, reaction mechanisms and optimal conditions for successful synthesis. Since the obtained products will be applied for biological and medical studies by COST specialists, they should be free from impurities including residual metal catalyst. Therefore, in the project special attention will be paid on reaction conditions and catalyst immobilization/inclusion to design experimental procedure providing metal free products.
Description of tasks: Analysis of data collected in our team and analysis of literature data. Synthesis of catalysts. Performing catalytic reactions with
copper-based catalysts and discovery new catalytic reactions based on data analysis. Preparation of reports and manuscripts.
R1
1
Project manager: prof. Ryszard Ostaszewski
Phone: +48 22 3432054
e-mail: ryszard.ostaszewski@icho.edu.pl
Required competences: knowledge of organic synthesis, ability to work with scientific literature, ability to use scientific databases (REAXYS, ScienceFinder), independent analysis of literature data
Desirable competences: creativity, independence and responsibility, ability to use databases describing enzymes (BRENDA, etc.), knowledge of biochemistry, basic medicinal chemistry.
Along with the required documents, please send a scan of a signed consent to the processing of personal data available below.
2023-01-04 time: 23:59 [GMT+1, Poland Time Zone]
2023-02-13
Envisaged job starting date: 01.03.2023 r.
Applications should be sent by e-mail.
Secretariat
Institute of Organic Chemistry of the Polish Academy of Sciences
Kasprzaka 44/52 Street
01-224 Warsaw
Phone: +48 22 631 8788
e-mail: rekrutacja@icho.edu.pl
ATTENTION! In the title of the e-mail, please enter “Recruitment – Ryszard Ostaszewski”
Candidates who are not PhD Students of the Doctoral School must take part in the recruitment process to the Warsaw-4-PhD Doctoral School! Details available here!
“Design of functional organic memristors (DOOM)”
The student is expected to fine-tune the structures of molecular devices by means of in-silico modelling. In addition, they are expected to perform post-processing analyses on the wavefunction such as QTAIM, ELF, and IQA analyses.
R1
1
This is a unique opportunity to develop a novel type of molecular devices in a dynamic environment in close collaboration with a team of researchers spanning from physicists to synthetic organic chemists. This work is the first of its type; therefore, the student will have the opportunity to gain experience in a field that is about to open.
Project manager: dr Cina Foroutan-Nejad
Phone: +48 573 537 340
e-mail: cforoutan-nejad@icho.edu.pl
Required competences
Desirable competences
Along with the required documents, please send a scan of a signed consent to the processing of personal data available below.
2023-01-04 time: 23:59 [GMT+1, Poland Time Zone]
2023-02-13
Envisaged job starting date: 01.03.2023 r.
Applications should be sent by e-mail.
Secretariat
Institute of Organic Chemistry of the Polish Academy of Sciences
Kasprzaka 44/52 Street
01-224 Warsaw
Phone: +48 22 631 8788
e-mail: rekrutacja@icho.edu.pl
ATTENTION! In the title of the e-mail, please enter “Recruitment – Cina Foroutan-Nejad”
Candidates who are not PhD Students of the Doctoral School must take part in the recruitment process to the Warsaw-4-PhD Doctoral School! Details available here!
“Ambipolar, bowl-shaped polyaromatic compounds with manifold, precisely arranged, nitrogen dopants. Unprecedented class of efficient OLED emitters (BOwLEDs).”
Description of tasks:
The scope of duties includes analysis of the literature on non-planar organic compounds, TADF active materials, the chemistry of nanografenes, aromatic compounds and transformations enabling the implementation of the proposed synthetic pathways, optimization and carrying out of organic syntheses on a laboratory and preparative scale, purification and isolation of compounds intermediates by means of precipitation, maceration, crystallization, column chromatography. Identification of obtained compounds by using spectroscopic tools and critical analysis of obtained results, their presentation (team seminars) and written two-weeks reports. PhD student will visit a laboratory of Prof. Przemysław Data to get practical knowledge regarding OLEDs fabrication and their analysis. Furthermore, prospective PhD students will be obliged to take a part and pass dedicated lectures (Warsaw4PhD doctoral school), soft-skills, and English courses. She/He will be responsible for combining and preparing supplementary information for manuscripts
R1
1
Project manager: Marcin Lindner, PhD
Phone: 22 343 2106
e-mail: marcin.lindner@icho.edu.pl
required competences
desirable competences
Along with the required documents, please send a scan of a signed consent to the processing of personal data available below.
2023-01-04 time: 23:59 [GMT+1, Poland Time Zone]
2023-02-13
Envisaged job starting date: 2023-03-01
Applications should be sent by e-mail.
Secretariat
Institute of Organic Chemistry of the Polish Academy of Sciences
Kasprzaka 44/52 Street
01-224 Warsaw
Phone: +48 22 631 8788
e-mail: rekrutacja@icho.edu.pl
ATTENTION! In the title of the e-mail, please enter “Recruitment – Marcin Lindner”
Candidates who are not PhD Students of the Doctoral School must take part in the recruitment process to the Warsaw-4-PhD Doctoral School! Details available here!
“Novel tricyclic glycomimetics as DC-SIGN receptor ligands”
Description of tasks: Synthesis and characterization of organic compounds as well as investigation of ligand-receptor binding properties using nuclear magnetic resonance (NMR) and isothermal titration calorimetry (ITC) methods. The work will be carried out in close collaboration with other PhD students, post-docs, and other co-investigators from IOC PAS and collaborative Polish and foreign institutions.
R1
1
Project manager: dr hab. Mykhaylo Potopnyk
Phone: +4822 3432132
e-mail: mykhaylo.potopnyk@icho.edu.pl
required competences
desirable competences
Along with the required documents, please send a scan of a signed consent to the processing of personal data available below.
2023-01-04 time: 23:59 [GMT+1, Poland Time Zone]
2023-02-13
Envisaged job starting date: 2023-03-01
Applications should be sent by e-mail.
Secretariat
Institute of Organic Chemistry of the Polish Academy of Sciences
Kasprzaka 44/52 Street
01-224 Warsaw
Phone: +48 22 631 8788
e-mail: rekrutacja@icho.edu.pl
ATTENTION! In the title of the e-mail, please enter “Recruitment – Mykhaylo Potopnyk”
Candidates who are not PhD Students of the Doctoral School must take part in the recruitment process to the Warsaw-4-PhD Doctoral School! Details available here!
“Self- or a directing group-aided remote C(sp3)-H functionalization of difunctional compounds”
The announced research project, funded by Polish National Science Center, is devoted to develop novel methods for self- and a directing group aided C(sp3)-H functionalization of simple bi- and polyfunctional organic molecules. Most of the efforts will be put on the development mild and versatile protocols under modern radical photoredox or electrochemical conditions. Previous experience with organic photochemistry and/or electrochemistry will be an additional asset.
The PhD candidate (PDC) will be responsible for synthesizing, depositing, and characterizing of the starting materials and intermediates, followed by an optimization of reaction conditions for model transformations of radical initiated remote C(sp3)-H functionalization of bi- and polyfuntional organic compounds. In extension, the PDC will investigate a scope of the developed protocols, including starting material variations, reaction condition variation (photoredox, electrochemical, transition-metal catalyzed process). Key efforts will be put on an investigation of asymmetric mode of the investigated C-H functionalization along with application studies devoted to synthesis of the selected bioactive or medicinally important molecule by using investigated process. Complementary theoretical studies on reaction mechanisms may be performed by the PDS or as part of a collaboration, depending on the scholar’s interests. To a certain degree, the PDC will be given intellectual freedom in defining their research.
The PhD candidate will also participate in the Institute scientific life by attending to group and institute seminars and lectures. The PhD candidate will also attend to advanced course devoted to modern organic chemistry and spectroscopy.
R1
1
Terms of employment: scholarship for 40 months with the possibility of extension – stipend (including employer’s costs) 5,000 PLN per month (~4600 PLN gross) paid from NSC grant
Benefits: private medical care package, co-financing of sports cards, possibility of accommodation at the Doctoral Hotel
Career development opportunities:
Project manager: dr hab. Sebastian Stecko
Phone: +4822 343 2137 or +4822 343 3065
e-mail: sebastian.stecko@icho.edu.pl
Website: The Stecko Research Group website
A prerequisite for qualifying for the project is the PhD student status at the Warsaw PhD School in Natural and BioMedical Sciences (the interviews will be held from 24.01.2023 r. to 02.02.2023 r.; the deadline for submitting documents to the doctoral school is January 4th, 2023), details are available on the Warsaw4PhD School website as well as the Institute of Organic Chemistry PAS website.
mandatory requirements:
optional requirements:
Along with the required documents, please send a scan of a signed consent to the processing of personal data available below.
2023-01-04 time: 23:59 [GMT+1, Poland Time Zone]
2023-02-13
Envisaged job starting date: February/March 2023
Applications should be sent by e-mail.
Secretariat
Institute of Organic Chemistry of the Polish Academy of Sciences
Kasprzaka 44/52 Street
01-224 Warsaw
Phone: +48 22 631 8788
e-mail: rekrutacja@icho.edu.pl
ATTENTION! In the title of the e-mail, please enter “Recruitment PhD – Sebastian Stecko”
Candidates who are not PhD Students of the Doctoral School must take part in the recruitment process to the Warsaw-4-PhD Doctoral School! Details available here!
“CO2CHEM – REDOX-NEUTRAL PHOTOCATALYTIC C-H CARBOXYLATION OF HYDROCARBONS WITH CO2“
Description of tasks: Studies on a model C-H carboxylation of aliphatic hydrocarbons via single electron-reduction of CO2-evaluation of various dyes; synthesis of cobalt complexes, evaluation of their catalytic efficacy photo-organo-metal catalysed C-H carbonylation with CO generated in situ, training PhD student
R2/R3
1
Terms of employment: full time, temporary, 12 months with the possibility to be extended up to 36 months total, gross salary (including employer’s costs) 10,000 PLN per month (~ 8 300 PLN gross);
Benefits: private medical care package
Career development opportunities:
Project manager: Dorota Gryko
Phone: +48 22 343 20 51
e-mail: dorota.gryko@icho.edu.pl
required competences
desirable competences
Along with the required documents, please send a scan of a signed consent to the processing of personal data available below.
2022-12-31 23:59
2023-01-18
Envisaged job starting date: 01.02.2023
Please send your applications to e-mail: rekrutacja@icho.edu.pl
Secretariat
Institute of Organic Chemistry of the Polish Academy of Sciences
Kasprzaka 44/52 Street
01-224 Warsaw
Phone: +48 22 631 8788
ATTENTION! In the title of the e-mail, please enter “Recruitment – Dorota Gryko”
“Modulated nanozymes: hybrid catalysts on nanoparticles exhibiting long-range substrate selectivity”
Description of tasks: We seek an experienced, highly enthusiastic computational or theoretical chemist to work on computer-assisted design of nanocatalysts and catalysts within the project of the National Science Center “Modulated nanozymes: hybrid catalysts on nanoparticles showing long-range substrate selectivity”. The Candidate will apply the methods of quantum mechanics, molecular dynamics, and/or machine learning to study and design novel catalytic systems and nanosystems. The Candidate will work within a vibrant group of organic chemists and theorists, and will participate in the process of preparing results for publication and presentation.
R2
2
Project manager: Bartosz Grzybowski
Phone: +48 22 343 20 88
e-mail: nanogrzybowski@gmail.com
Along with the required documents, please send a scan of a signed consent to the processing of personal data available below.
2022-11-30 15:00
2022-12-09
Envisaged job starting date: 15.12.2022 r.
Please send your applications to e-mail: rekrutacja@icho.edu.pl
Secretariat
Institute of Organic Chemistry of the Polish Academy of Sciences
Kasprzaka 44/52 Street
01-224 Warsaw
Phone: +48 22 631 8788
ATTENTION! In the title of the e-mail, please enter “Recruitment – Bartosz Grzybowski“
“Degradation of hazardous chemical compounds into valuable building blocks: from computer-planned routes to experimental validation”
This project aims to address one important aspect of sustainable chemistry, namely, discovery of novel methodologies to convert hazardous or unwanted chemical waste into useful products. We will provide new strategies leading to valuable building blocks based on degradation protocols. Such multistep chemical and chemo-enzymatic pathways designed by the computer will be selected and executed in the laboratory.
Description of tasks:Person employed in this position will be responsible for performing computational calculations, verification that pathways are novel (comparison with databases of published reactions), planning experiments, cultivation and harvesting of microorganisms relevant to biocatalytic steps, performing chemical and mirobiological experiments in the chemical laboratory, analysis and identification of chemical compounds, analysis of obtained results, participation in the writing of manuscripts, presentation of project results.
R2
1
Project manager: dr Anna Żądło-Dobrowolska
Phone: +48 22 343 21 17
e-mail: azadlo@icho.edu.pl
Along with the required documents, please send a scan of a signed consent to the processing of personal data available below.
2022-12-04 15:00
2022-12-16
Envisaged job starting date: 01.01.2023 r.
Please send your applications to e-mail: rekrutacja@icho.edu.pl
Secretariat
Institute of Organic Chemistry of the Polish Academy of Sciences
Kasprzaka 44/52 Street
01-224 Warsaw
Phone: +48 22 631 8788
ATTENTION! In the title of the e-mail, please enter “Recruitment – Anna Zadlo-Dobrowolska“
“Autonomous discovery, development and optimization of organocatalytic reactions through intelligent chemical robots”
Chirality plays an important role in nature, as molecules of different chirality can exhibit vastly different properties. A large part of the field of chemical catalysis, and in particular of organocatalysis, is devoted to the selective synthesis of chiral molecules. However, despite the huge progress made in recent decades, we are still far from being able to efficiently design the synthesis of any chiral molecule. Usually, the development of new (organo)catalytic methods requires extensive and time-consuming optimization, which is usually performed manually. Therefore new enabling technologies are needed to speed up this process. Automation and robotic approaches have started to play an important role in the chemical sciences. The use of automated approaches can speed up the research process, make the experiments more repeatable and free researchers from repetitive tasks, so they can focus on the design of new transformations. In this project, we aim to investigate the field of organocatalysis with chemical automation and robotics that will ultimately be guided by artificial intelligence methods.
Description of tasks:
The successful Candidate will work on several goals:
R2
1
Project manager: Dr Jaroslaw Granda
Phone: +48 22 343 2021; +48 697 231 776
e-mail: jaroslaw.granda@icho.edu.pl
Along with the required documents, please send a scan of a signed consent to the processing of personal data available below.
2022-12-05 23:59
2022-12-16
Envisaged job starting date: 01.01.2023 r.
Please send your applications to e-mail: rekrutacja@icho.edu.pl
Secretariat
Institute of Organic Chemistry of the Polish Academy of Sciences
Kasprzaka 44/52 Street
01-224 Warsaw
Phone: +48 22 631 8788
ATTENTION! In the title of the e-mail, please enter “Recruitment – Jaroslaw Granda“
“New Molecular Architectures for Exploring Singlet Fission”
Description of tasks: We are looking for a motivated Post-doctoral Research Assistant to join a vibrant research group synthesizing and studying novel optoelectronic organic materials. Key responsibilities at this position will include the synthesis and analysis of polycyclic hydrocarbon-based materials, solving encountered synthetic problems, creating new ideas within the project scope, testing hypotheses, analyzing scientific data from a variety of sources, supervision of junior colleagues, regular reporting of the progress. During this appointment, you will gain a variety of transferable skills necessary in academic and industrial environments.
R2
1
Project manager: Dr. Przemyslaw Gawel
Phone: +48 22 343 2129
e-mail: pgawel@icho.edu.pl
Along with the required documents, please send a scan of a signed consent to the processing of personal data available below.
2022-10-31 23:59
2022-11-20
Envisaged job starting date: 01.01.2023 r.
Please send your applications to e-mail: rekrutacja@icho.edu.pl
Secretariat
Institute of Organic Chemistry of the Polish Academy of Sciences
Kasprzaka 44/52 Street
01-224 Warsaw
Phone: +48 22 631 8788
ATTENTION! In the title of the e-mail, please enter “Recruitment – Przemyslaw Gawel“
Description of tasks: performing synthetic experiments in the lab, writing manuscripts, helping with writing the reports, supervising students and PhD-students
R4
1
Project manager: prof. Daniel T. Gryko
Phone: (22) 3432321
e-mail: dtgryko@icho.edu.pl
Required competences: experience in synthetic organic chemistry
Desirable competences: experience in heterocyclic chemistry, experience in multicomponent reactions
Along with the required documents, please send a scan of a signed consent to the processing of personal data available below.
The Candidate will be selected on the basis of the submitted application.
29.09.2022 17:00
30.09.2022
Envisaged job starting date: 01.10.2022
Applications should be send by e-mail.
Secretariat
Institute of Organic Chemistry of the Polish Academy of Sciences
Kasprzaka 44/52 Street
01-224 Warsaw
Phone: +48 22 631 8788
e-mail: rekrutacja@icho.edu.pl
ATTENTION! In the title of the e-mail, please enter “Recruitment – Daniel Gryko”
“Photoelectrocatalysis in parallel, paired electrolysis – zero-waste approach for modern organic chemistry“
Independent research tasks as part of the NSC project: Photoelectrocatalysis in parallel, paired electrolysis – zero-waste approach for modern organic chemistry in the field of foto and electrocatalysis – preparation of publication material and presentation
R2
2
Project manager: dr Katarzyna Rybicka-Jasińska
Phone: +48 692 639 333, 23432102
e-mail: katarzyna.rybickajasinska@gmail.com
Required competences:
Desirable competences:
Along with the required documents, please send a scan of a signed consent to the processing of personal data available below.
2022-10-15 14:00
2022-11-10
Envisaged job starting date: 01.12.2022
Secretariat
Institute of Organic Chemistry of the Polish Academy of Sciences
Kasprzaka 44/52 Street
01-224 Warsaw
Phone: +48 22 631 8788
e-mail: rekrutacja@icho.edu.pl
ATTENTION! In the title of the e-mail, please enter “Recruitment – Katarzyna Rybicka-Jasinska“
“Design of functional organic memristors (DOOM)”
The student is expected to fine-tune the structures of molecular devices by means of in-silico modelling. In addition, they are expected to perform post-processing analyses on the wavefunction such as QTAIM, ELF, and IQA analyses.
R1
1
This is a unique opportunity to develop a novel type of molecular devices in a dynamic environment in close collaboration with a team of researchers spanning from physicists to synthetic organic chemists. This work is the first of its type; therefore, the student will have the opportunity to gain experience in a field that is about to open.
Project manager: dr Cina Foroutan-Nejad
Phone: +48 573 537 340
e-mail: cforoutan-nejad@icho.edu.pl
Required competences
Desirable competences
Along with the required documents, please send a scan of a signed consent to the processing of personal data available below.
2022-08-10 23:59
2022-09-22
Envisaged job starting date: 01.10.2022
Secretariat
Institute of Organic Chemistry of the Polish Academy of Sciences
Kasprzaka 44/52 Street
01-224 Warsaw
Phone: +48 22 631 8788
e-mail: rekrutacja@icho.edu.pl
ATTENTION! In the title of the e-mail, please enter “Recruitment – Cina Foroutan-Nejad”
Candidates who are not PhD Students of the Doctoral School must take part in the recruitment process to the Warsaw-4-PhD Doctoral School!
“Autonomous discovery, development and optimization of organocatalytic reactions through intelligent chemical robots”
Chirality plays an important role in nature, as molecules of different chirality can exhibit vastly different properties. A large part of the field of chemical catalysis, and in particular of organocatalysis, is devoted to the selective synthesis of chiral molecules. However, despite the huge progress made in recent decades, we are still far from being able to efficiently design the synthesis of any chiral molecule. Usually, the development of new (organo)catalytic methods requires extensive and time-consuming optimization, which is usually performed manually. Therefore new enabling technologies are needed to speed up this process. Automation and robotic approaches have started to play an important role in the chemical sciences. The use of automated approaches can speed up the research process, make the experiments more repeatable and free researchers from repetitive tasks, so they can focus on the design of new transformations. In this project, we aim to investigate the field of organocatalysis with chemical automation and robotics that will ultimately be guided by artificial intelligence methods.
Description of tasks: The successful Candidate will work on several goals:
R1
1
Project manager: Dr Jaroslaw Granda
Phone: +48 22 343 2021; +48 697 231 776
e-mail: jaroslaw.granda@icho.edu.pl
required competences
desirable competences
Along with the required documents, please send a scan of a signed consent to the processing of personal data available below.
2022-08-10 23:59
2022-09-20
Envisaged job starting date: 01.10.2022
Secretariat
Institute of Organic Chemistry of the Polish Academy of Sciences
Kasprzaka 44/52 Street
01-224 Warsaw
Phone: +48 22 631 8788
e-mail: rekrutacja@icho.edu.pl
ATTENTION! In the title of the e-mail, please enter “Recruitment – Jaroslaw Granda”
Candidates who are not PhD Students of the Doctoral School must take part in the recruitment process to the Warsaw-4-PhD Doctoral School!
“Mechanochemical self-assembly of anion-sealed molecular capsules”
Synthesis of macrocyclic compounds, mechanochemical experiments, NMR experiments, interpretation of NMR, ECD and other spectral data, complexation experiments and interpretation of complexation data. Preparation of data for publication.
R1
1
Project manager: prof. Agnieszka Szumna
Phone: +48 22 343 22 03
e-mail: agnieszka.szumna@icho.edu.pl
Required competences
Desirable competences
Along with the required documents, please send a scan of a signed consent to the processing of personal data available below.
2022-08-10 12:59
2022-09-22
Envisaged job starting date: 01.10.2022
Secretariat
Institute of Organic Chemistry of the Polish Academy of Sciences
Kasprzaka 44/52 Street
01-224 Warsaw
Phone: +48 22 631 8788
e-mail: rekrutacja@icho.edu.pl
ATTENTION! In the title of the e-mail, please enter “Recruitment – Agnieszka Szumna”
Candidates who are not PhD Students of the Doctoral School must take part in the recruitment process to the Warsaw-4-PhD Doctoral School!
“CO2CHEM – redox-neutral photocatalytic C-H carboxylation of hydrocarbons with CO2“
The general goal of this proposal is to develop the synthetic and mechanistic basis for the photocatalytic, redox-neutral C-H carboxylation of saturated hydrocarbons with CO2. To address this challenge, we propose new synthetic strategies based on photocatalytically generated alkyl radicals and earth-abundant metal complexes to provide C-H carboxylation in an overall redox-neutral process.
The project will be realized in strong collaboration with prof. B König from the Faculty of Chemistry and Pharmacy, University of Regensburg, Germany.
In particular, the main tasks will involve:
R1
1
Terms of employment: scholarship for 48 months – stipend (including employer’s costs) 5,000 PLN per month (~4600 PLN gross) paid from grant for 27 months + stipend paid by IOC PAS after the end of the grant
Benefits: private medical care package, access to the dormitory for PhD students
Career development opportunities:
Project manager: Dorota Gryko
Phone: +48 22 343 20 51
e-mail: dorota.gryko@icho.edu.pl
Required competences
Desirable competences
Along with the required documents, please send a scan of a signed consent to the processing of personal data – template available below.
2022-08-10 12:59
2022-09-22
Envisaged job starting date: 01.10.2022
Secretariat
Institute of Organic Chemistry of the Polish Academy of Sciences
Kasprzaka 44/52 Street
01-224 Warsaw
Phone: +48 22 631 8788
e-mail: rekrutacja@icho.edu.pl
ATTENTION! In the title of the e-mail, please enter “Recruitment – Dorota Gryko”
Candidates who are not PhD Students of the Doctoral School must take part in the recruitment process to the Warsaw-4-PhD Doctoral School!
“Novel tricyclic glycomimetics as DC-SIGN receptor ligands”
Description of tasks: Synthesis and characterization of organic compounds; molecular docking and molecular dynamic calculation of the ligand-receptor interactions; investigation of ligand-receptor binding properties using nuclear magnetic resonance (NMR) and isothermal titration calorimetry (ITC) methods. The work will be carried out in close collaboration with PhD students and other co-investigators.
R2/R3
1
Project manager: dr hab. Mykhaylo Potopnyk
Phone: +4822 3432132
e-mail: mykhaylo.potopnyk@icho.edu.pl
required competences
desirable competences
Along with the required documents, please send a scan of a signed consent to the processing of personal data available below.
2022-08-05 23:59
2022-08-22
Envisaged job starting date: 2022-09-01
Applications should be sent by e-mail.
Secretariat
Institute of Organic Chemistry of the Polish Academy of Sciences
Kasprzaka 44/52 Street
01-224 Warsaw
Phone: +48 22 631 8788
e-mail: rekrutacja@icho.edu.pl
ATTENTION! In the title of the e-mail, please enter “Recruitment – Mykhaylo Potopnyk”
“Novel tricyclic glycomimetics as DC-SIGN receptor ligands”
Description of tasks: Synthesis and characterization of organic compounds as well as investigation of ligand-receptor binding properties using nuclear magnetic resonance (NMR) and isothermal titration calorimetry (ITC) methods. The work will be carried out in close collaboration with other PhD students, post-docs, and other co-investigators from IOC PAS and collaborative Polish and foreign institutions.
R1
2
Project manager: dr hab. Mykhaylo Potopnyk
Phone: +4822 3432132
e-mail: mykhaylo.potopnyk@icho.edu.pl
required competences
desirable competences
Along with the required documents, please send a scan of a signed consent to the processing of personal data available below.
2022-08-10 time: 12:59 [GMT+1, Poland Time Zone]
2022-09-20
Envisaged job starting date: 2022-10-01
Applications should be sent by e-mail.
Secretariat
Institute of Organic Chemistry of the Polish Academy of Sciences
Kasprzaka 44/52 Street
01-224 Warsaw
Phone: +48 22 631 8788
e-mail: rekrutacja@icho.edu.pl
ATTENTION! In the title of the e-mail, please enter “Recruitment – Mykhaylo Potopnyk”
Candidates who are not PhD Students of the Doctoral School must take part in the recruitment process to the Warsaw-4-PhD Doctoral School!
“Chemoenzymatic cascades of new Cu and Pd reactions of significant application potential”
Currently, an increase in the incidence of cancer is observed, thus it is extremely important to eliminate or limit them. One of types of cancer is multidrug resistant (MDR) solid tumors. This is the subject of COST action CA17104. The key challenge of this action is an identification of a new diagnostic/predictive biomarkers, producing new and safe compounds applicable to personalized treatments of MDR tumors. In order to achieve such goal, we need to design new synthetic protocols providing organic compounds of defined structure, free from any impurities. Therefore, during the realization of project we will study a new type of organic reactions catalyzed by copper salts, which provide molecules of high activity towards MDR. To achieve success, we need to know reaction scope and limitations, reaction mechanisms and optimal conditions for successful synthesis. Since the obtained products will be applied for biological and medical studies by COST specialists, they should be free from impurities including residual metal catalyst. Therefore, in the project special attention will be paid on reaction conditions and catalyst immobilization/inclusion to design experimental procedure providing metal free products.
Description of tasks: Analysis of data collected in our team and analysis of literature data. Synthesis of catalysts. Performing catalytic reactions with
copper-based catalysts and discovery new catalytic reactions based on data analysis. Preparation of reports and manuscripts.
R1
2
Project manager: prof. Ryszard Ostaszewski
Phone: +48 22 3432054
e-mail: ryszard.ostaszewski@icho.edu.pl
Required competences: knowledge of organic synthesis, ability to work with scientific literature, ability to use scientific databases (REAXYS, ScienceFinder), independent analysis of literature data
Desirable competences: creativity, independence and responsibility, ability to use databases describing enzymes (BRENDA, etc.), knowledge of biochemistry, basic medicinal chemistry.
Along with the required documents, please send a scan of a signed consent to the processing of personal data available below.
10.08.2022
20.09.2022
Envisaged job starting date: 01.10.2022
Applications should be sent by e-mail.
Secretariat
Institute of Organic Chemistry of the Polish Academy of Sciences
Kasprzaka 44/52 Street
01-224 Warsaw
Phone: +48 22 631 8788
e-mail: rekrutacja@icho.edu.pl
ATTENTION! In the title of the e-mail, please enter “Recruitment – Ryszard Ostaszewski”
Candidates who are not PhD Students of the Doctoral School must take part in the recruitment process to the Warsaw-4-PhD Doctoral School!
“Self- or a directing group-aided remote C(sp3)-H functionalization of difunctional compounds”
The announced research project, funded by Polish National Science Center, is devoted to develop novel methods for self- and a directing group aided C(sp3)-H functionalization of simple bi- and polyfunctional organic molecules. Most of the efforts will be put on the development mild and versatile protocols under modern radical photoredox or electrochemical conditions. Previous experience with organic photochemistry and/or electrochemistry will be an additional asset.
The PhD candidate (PDC) will be responsible for synthesizing, depositing, and characterizing of the starting materials and intermediates, followed by an optimization of reaction conditions for model transformations of radical initiated remote C(sp3)-H functionalization of bi- and polyfuntional organic compounds. In extension, the PDC will investigate a scope of the developed protocols, including starting material variations, reaction condition variation (photoredox, electrochemical, transition-metal catalyzed process). Key efforts will be put on an investigation of asymmetric mode of the investigated C-H functionalization along with application studies devoted to synthesis of the selected bioactive or medicinally important molecule by using investigated process. Complementary theoretical studies on reaction mechanisms may be performed by the PDS or as part of a collaboration, depending on the scholar’s interests. To a certain degree, the PDC will be given intellectual freedom in defining their research.
The PhD candidate will also participate in the Institute scientific life by attending to group and institute seminars and lectures. The PhD candidate will also attend to advanced course devoted to modern organic chemistry and spectroscopy.
R1
2
Terms of employment: scholarship for 48 months – stipend (including employer’s costs) 5,000 PLN per month (~4600 PLN gross) paid from NSC grant
Benefits: private medical care package, co-financing of sports cards, possibility of accommodation at the Doctoral Hotel
Career development opportunities:
Project manager: dr hab. Sebastian Stecko
Phone: +4822 343 2137 or +4822 343 3065
e-mail: sebastian.stecko@icho.edu.pl
Website: The Stecko Research Group website
A prerequisite for qualifying for the project is the PhD student status at the Warsaw PhD School in Natural and BioMedical Sciences (the interviews will be held from 05 September 2022 to 15 September 2022; the deadline for submitting documents to the doctoral school is August 10th, 2022), details are available on the Warsaw4PhD School website Doctoral website as well as the Institute of Organic Chemistry PAS website.
mandatory requirements:
optional requirements:
Along with the required documents, please send a scan of a signed consent to the processing of personal data available below.
2022-08-10 time: 12:59 [GMT+1, Poland Time Zone]
2022-09-20
Envisaged job starting date: October 2022
Applications should be sent by e-mail.
Secretariat
Institute of Organic Chemistry of the Polish Academy of Sciences
Kasprzaka 44/52 Street
01-224 Warsaw
Phone: +48 22 631 8788
e-mail: rekrutacja@icho.edu.pl
ATTENTION! In the title of the e-mail, please enter “Recruitment PhD – Sebastian Stecko”
Candidates who are not PhD Students of the Doctoral School must take part in the recruitment process to the Warsaw-4-PhD Doctoral School!
“CO2CHEM – REDOX-NEUTRAL PHOTOCATALYTIC C-H CARBOXYLATION OF HYDROCARBONS WITH CO2”
Studies on a model C-H carboxylation of aliphatic hydrocarbons via single electron-reduction of CO2-evaluation of various dyes; synthesis of cobalt complexes, evaluation of their catalytic efficacy photo-organo-metal catalysed C-H carbonylation with CO2 generated in situ, training PhD students.
R2/R3
1
Terms of employment: full time, temporary, 12 months with the possibility to be extended up to 36 months total, gross salary (including employer’s costs)
10,000 PLN per month (~ 8 300 PLN gross);
Benefits: private medical care package
Career development opportunities:
Project manager: prof. Dorota Gryko
Phone: +48 22 343 20 51
e-mail: dorota.gryko@icho.edu.pl
required competences
desirable competences
Along with the required documents, please submit (or send a scan) a signed consent to the processing of personal data available below.
2022-08-05 23:59
2022-08-26
Envisaged job starting date: 01.09.2022
Applications should be sent by e-mail.
Secretariat
Institute of Organic Chemistry of the Polish Academy of Sciences
Kasprzaka 44/52 Street
01-224 Warsaw
Phone: +48 22 631 8788
e-mail: rekrutacja@icho.edu.pl
ATTENTION! In the title of the e-mail, please enter “Recruitment – Dorota Gryko”
“Photoelectrocatalysis in parallel, paired electrolysis – zero-waste approach for modern organic chemistry“
Independent research tasks as part of the NSC project: Photoelectrocatalysis in parallel, paired electrolysis – zero-waste approach for modern organic chemistry in the field of foto and electrocatalysis – preparation of publication material and presentation
R2
1
Project manager: dr Katarzyna Rybicka-Jasińska
Phone: +48 692 639 333, 23432102
e-mail: katarzyna.rybickajasinska@gmail.com
Required competences:
Desirable competences:
Along with the required documents, please submit (or send a scan) a signed consent to the processing of personal data available at: https://www.icho.edu.pl/en/cooperations/career/
2022-08-01 14:00
2022-08-20
Envisaged job starting date: 01.09.2022
Secretariat
Institute of Organic Chemistry of the Polish Academy of Sciences
Kasprzaka 44/52 Street
01-224 Warsaw
Phone: +48 22 631 8788
e-mail: rekrutacja@icho.edu.pl
ATTENTION! In the title of the e-mail, please enter “Recruitment – Katarzyna Rybicka-Jasinska“
Self- or a directing group-aided remote C(sp3)-H functionalization of difunctional compounds
The focus of this funded by Polish National Science Center project is developing novel methods for self- and a directing group aided C(sp3)-H functionalization of simple bi- and polyfunctional organic molecules. Most of the efforts will be put on the development mild and versatile protocols under modern radical photoredox or electrochemical conditions. Previous experience with organic photochemistry and/or electrochemistry will be an additional asset.
The post-doctorate scholar (PDS) will be responsible for synthesizing, depositing, and characterizing of the starting materials and intermediates, followed by an optimization of reaction conditions for model transformations of radical initiated remote C(sp3)-H functionalization of bi- and polyfuntional organic compounds. In extension, the PDS will investigate a scope of the developed protocols, including starting material variations, reaction condition variation (photoredox, electrochemical, transition-metal catalyzed process). Key efforts will be put on an investigation of asymmetric mode of the investigated C-H functionalization along with application studies devoted to synthesis of the selected bioactive or medicinally important molecule by using investigated process., . Complementary theoretical studies on reaction mechanisms may be performed by the PDS or as part of a collaboration, depending on the scholar’s interests. To a certain degree, the PDS will be given intellectual freedom in defining their research.
The post-doctorate scholar will also participate in the education of junior research staff, providing advice and support in designing synthesis, and in solving problems and troubleshooting during the realization of the project tasks.
R2
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Project manager: dr hab. Sebastian Stecko
Phone: +4822 343 2137 or +4822 343 3065
e-mail: sebastian.stecko@icho.edu.pl
Website: The Stecko Research Group website
Required competences
* This period is extended by duration of maternity/paternity leaves according to the Polish National Science Center rules.
Desirable competences
Along with the required documents, please submit (or send a scan) a signed consent to the processing of personal data available at: https://www.icho.edu.pl/en/cooperations/career/
*The PES (Professional Experience and Skills Form) is available online and is intended to become familiar with Candidate’s previous experience and skills in the field of practical organic synthesis. The questions contained in the form concern the level of knowledge of standard and advanced laboratory techniques, the level of knowledge of analytical techniques and spectral methods. Note, please give reliable answers to the questions contained in the PES form, as they will be used and verified during the interviews.
After completing the PES form on the indicated web page and clicking “submit” your answers will be sent directly to us.
Do not forget to send the rest of the required documents to the e-mail address: rekrutacja@icho.edu.pl
31-08-2022, 12:59
21-09-2022
Envisaged job starting date: October/November 2022
Institute of Organic Chemistry of the Polish Academy of Sciences
Kasprzaka 44/52 Street
01-224 Warsaw
Phone: +48 22 631 8788
e-mail: rekrutacja@icho.edu.pl
ATTENTION! In the title of the e-mail, please enter “Recruitment – Sebastian Stecko”
Solid-state circular dichroism (CD) spectroscopies as a tool for supporting the development of medicinal chemistry
The work will consist of conducting the assigned research tasks as part of the project financed by the Polish National Science Center: “Solid-state circular dichroism (CD) spectroscopies as a tool for supporting the development of medicinal chemistry” in the field of circular dichroism measurements, analysis and interpretation of experimental results, preparation of materials for publication and presentation.
R2/R3
1
Project manager: Dr Marcin Górecki
Phone: (22) 3432212
e-mail: marcin.gorecki@icho.edu.pl
Required competences
Desirable competences
Along with the required documents, please submit (or send a scan) a signed consent to the processing of personal data available at: https://www.icho.edu.pl/en/cooperations/career/
The candidate will be selected on the basis of the submitted application.
2022-08-08 15:00
2022-08-08
Envisaged job starting date: 01.09.2022
Secretariat
Institute of Organic Chemistry of the Polish Academy of Sciences
Kasprzaka 44/52 Street
01-224 Warsaw
Phone: +48 22 631 8788
e-mail: rekrutacja@icho.edu.pl
ATTENTION! In the title of the e-mail, please enter “Recruitment – Marcin Górecki”