Job Offers

Project/Grant title

Control of regio- and stereoselectivity of hydro- and carbofluoromethylation of alkynes via a sequence of hydro- or carbometallation and C-M functionalization

Job description

Post-doc position (12 months) is available. The project is aimed at development of methods for regio- and stereoselective fluoroalkylations of alkynes. We are seeking a highly motivated candidate with strong background in synthetic organic chemistry, transition metal catalysis or organometalic chemistry.

Researcher profile

R2/R3

Number of positions available

1

Offer

Terms of employment: full time, temporary, 12 months, gross salary (including employer’s costs)
10,000 PLN per month (~ 8 300 PLN gross)

Benefits: private medical care package, co-financing of sports cards

Career development opportunities: work in a young, dynamically developing team, access to research infrastructure, professional development in the field of organic chemistry and catalysis, the possibility of further professional development at the IOC PAS

Additional information

Project manager: Wojciech Chałądaj

e-mail: wojciech.chaladaj@icho.edu.pl

Requirements

required competencies

  • PhD In chemistry (or related science) obtained not earlier that 7 years before the start of employment in the project, or expected graduation of PhD by this date.
  • Strong background in synthetic organic chemistry, transition metal catalysis or organometallic chemistry
  • Good publication record in acclaimed journals.

desirable competences

  • Fluent written and verbal communication skills in English
  • Commitment and capacity for team work and critical thinking

List of required documents

  • Candidate’s Curriculum Vitae
  • description of scientific achievements, including a list of publications, ongoing projects (max 2 pages)
  • cover letter
  • letters of recommendation and references from previous employers/supervisors (2 letters)
  • consent to the processing of the Candidate’s personal data for the purposes of the competition

Along with the required documents, please submit (or send a scan) a signed consent to the processing of personal data available at: https://www.icho.edu.pl/en/cooperations/career/

Candidate evaluation criteria

  • scientific achievements measured by the quality of scientific publications or granted/pending patents
  • Candidate’s professional experience
  • creativity and independence in conducting research
  • career mobility (research internships, work in industry, change of scientific profile)
  • ability to work in a team
  • awards or distinctions
  • opinions about the Candidate contained in the letters of recommendation
  • language knowledge enabling conducting scientific research

Deadline for submitting applications

2024-02-18

Competition settlement date

2024-02-29

Envisaged job starting date: 01.04.2024

Attention! Changing the decision date. The new decision date is:

2024-03-20

Submitting applications

Secretariat

Institute of Organic Chemistry of the Polish Academy of Sciences

Kasprzaka 44/52 Street

01-224 Warsaw

Phone: +48 22 631 8788

e-mail: rekrutacja@icho.edu.pl

ATTENTION! In the title of the e-mail, please enter “Recruitment – Wojciech Chaladaj”

Project/Grant title

Palladium-catalyzed cascades for the rapid and enantioselective construction of polycyclic scaffolds of alkaloids and pseudo-natural products

Job description

The aim of the project is the development of palladium-catalyzed cascade reactions forming polycyclic nitrogen-containing structures, corresponding to the skeletons of natural alkaloids and their analogues. An important goal is to design and optimize these catalytic reactions also in enantioselective manner by performing them in the presence of chiral ligands. The work will involve multi-step syntheses of the precursors for the Pd-catalyzed cascade reactions, optimization of the cascade reactions, spectroscopic and HPLC analysis of the products, preparation of the results for publication and supervision of the younger members of the research team.

Researcher profile

R2

Number of positions available

1

Offer

  • Terms of employment: gross 11666.67 PLN (brutto/brutto) per month, net ca. 7000 PLN (ca. 1560 EUR), full time, 24 months duration
  • Benefits: medical care package, co-financing of sports cards
  • Career development opportunities: professional development in the field of organic synthesis and analysis of organic compounds, access to research infrastructure, the possibility of further professional development at the IOC PAS)

Additional information

Project manager:

Assoc. Professor Rafał Loska

Phone: +48 22 343 2108, +48 602 855 591

e-mail: rafal.loska@icho.edu.pl

www.icho.edu.pl/zespol/rafal-loska

Requirements

  • PhD degree in chemistry

 

Required competencies

  • good knowledge of organic chemistry
  • laboratory experience

Desirable competences

  • dedication to the project, interpersonal skills
  • good English language skills, sufficient for research work in chemistry

List of required documents

Candidate’s Curriculum Vitae

  • a brief description of scientific achievements, including a list of publications, ongoing projects, etc.
  • diplomas and certificates confirming qualifications, completed courses, completed training, etc.
  • cover letter
  • letters of recommendation and references from previous employers/supervisors
  • consent to the processing of the Candidates’ personal data for the purposes of the competition

Along with the required documents, please submit (or send a scan) a signed consent to the processing of personal data available at: https://www.icho.edu.pl/en/cooperations/career/

Candidate evaluation criteria

  • scientific achievements measured by the quality and quantity of scientific publications or granted/pending patents
  • Candidate’s professional experience
  • creativity and independence in conducting research
  • career mobility (research internships, work in industry, change of scientific profile)
  • ability to work in a team
  • awards or distinctions
  • opinions about the Candidate contained in the letters of recommendation
  • language knowledge enabling conducting scientific research

Deadline for submitting applications

12.02.2024

Competition settlement date

23.02.2024

Envisaged job starting date: 01.03.2024

Attention! Changing the decision date. The new decision date is:

2024-03-15

Submitting applications

Secretariat

Institute of Organic Chemistry of the Polish Academy of Sciences

Kasprzaka 44/52 Street

01-224 Warsaw

Phone: +48 22 343 23 20

e-mail: rekrutacja@icho.edu.pl

ATTENTION! In the title of the e-mail, please enter “Recruitment – Rafal Loska”

Project/Grant title

Artificial Intelligence meets Asymmetric Catalysis: a new pathway for catalyst optimization and discovery

Job description

The aim of the planned research is the artificial intelligence-assisted design and then experimental verification of new chiral Lewis acids containing zinc and magnesium ions as catalysts in selected organic reactions, in particular in the asymmetric reduction of the carbonyl group. Computer aided design of catalysts will require the analysis of data collected by our team during many years of work in the field of asymmetric synthesis and analysis of literature data. The aim of the research is also to implement a substantial database of results (both positive and negative) obtained in the course of previous research to solve the problems encountered at that time.

Description of tasks:

Background: Analysis of data collected in our team and analysis of literature data. Synthesis of catalysts. Performing catalytic reactions with zinc- and magnesium-based catalysts and discovery new catalytic reactions based on AI data analysis. Preparation of reports and manuscripts.

Researcher profile

R1

Number of positions available

1

Offer

Terms of employment: stipend (including employer’s costs) 5,000 PLN per month (~4,200 PLN gross), scholarship paid from grant for 30 months

Benefits: private medical care package, access to the dormitory for PhD students

Career development opportunities:

  • work in dynamic team,
  • access to research infrastructure,
  • professional development in the field of asymmetric synthesis,
  • the possibility of cooperation with foreign research centers,
  • the possibility of further professional development at the IOC PAS

Additional information

Project manager: prof. Jacek Młynarski

e-mail: jacek.mlynarski@icho.edu.pl

Requirements

  • Admission to doctoral studies at Warsaw PhD School in Natural and BioMedical Sciences (Warsaw-4-PhD) – https://warsaw4phd.eu/en/
  • master degree in chemistry;

Required competences

    • excellent knowledge of organic chemistry and organometallic chemistry,
    • data analysis and interpretation of experimental data (NMR, MS, UV/Vis), especially in trouble shooting during the research;
    • basic knowledge of rules and protocols valid in organic chemistry labs;
    • effective written and oral communication in English

Desirable competences

    • demonstrated experience in research work will be an asset;
    • creativity, independence, and responsibility
    • strong ability to work independently,

List of required documents

  • scientific curriculum vitae, including a list of scientific achievements (scholarships, publications, conference presentations, etc.);
  • motivation letter;
  • one recommendation letter;
  • a transcript of the grades/credits received; during the last stage of studies and grade point average.

Along with the required documents, please submit (or send a scan) a signed consent to the processing of personal data available at: https://www.icho.edu.pl/en/cooperations/career/

Candidate evaluation criteria

  • Candidate’s competence relevant to the project, knowledge of organic chemistry
  • scientific achievements measured by the quality and quantity of scientific publications
  • awards or distinctions
  • opinion about the Candidate contained in the letter of recommendation
  • language knowledge enabling conducting scientific research

Deadline for submitting applications

2023-10-15 23:59

Competition settlement date

2023-10-20

Envisaged job starting date: 2023-11-01

Submitting applications

Secretariat

Institute of Organic Chemistry of the Polish Academy of Sciences

Kasprzaka 44/52 Street

01-224 Warsaw

Phone: +48 22 631 8788

e-mail: rekrutacja@icho.edu.pl

ATTENTION! In the title of the e-mail, please enter “Recruitment – Jacek Mlynarski”

 

Project/Grant title

“Stereoselective dearomatization of nonactivated arenes via an „alkene walk” pathway: Rapid access to high-added value poly- and spirocyclic systems from readily available aromatic compounds”

Job description

The aim of this research proposal is to establish a new methodology for the stereoselective dearomatization of nonactivated arenes via the virtually unexplored retro-ene reaction of in situ generated benzylic diazenes (a so called “alkene walk” process), and subsequent transformation of the so formed active polyene species into chiral poly- and spirocyclic molecules. As a result, a new and versatile tool for the synthesis of high-value organic molecules from cheap and readily available benzylic alcohols, halides, aldehydes (in combination with organometallics) and monosilyl diazenes will be added to the organic chemist’s toolbox. Moreover, the possibility of synthesis of advanced polyaromatic systems via an additional re-aromatization process will be tested.

Stereoselective dearomatizations, especially in non-activated arenes, allowing conversion of readily available planar aromatic compounds into three-dimensionally complex molecules with precise control of reaction site, regio- and stereoselectivity has long been an exciting challenge in organic synthesis. Due to their high resonance stabilization energy, dearomatizations of nonactivated arenes usually require the use of stoichiometric amounts of expensive and toxic transition metal activators or elevated temperatures and harsh reaction conditions. This makes achieving high stereoselectivity in these processes very difficult. In our approach aromatic substrates are initially transformed into highly active polyenes which can then further derivatized using the broad spectrum of well-established stereoselective reactions of alkenes and dienes conducted under mild reaction conditions, resulting in highly stereoselective dearomatizations. Further advantages of the method include high availability of substrates (in the case of chiral derivatives in both enantiomeric forms in high optical purity) and high chemo- and stereodiversity of the obtained products.

The candidate will be responsible for synthesizing of the starting materials and polyene intermediates, followed by an studies on their selective of transformations into variety of poly- and spirocyclic systems using selected literature protocols. The candidate will also be responsible for recording and interpreting spectral data, designing experiments, and preparing reports and materials for publications. Complementary theoretical studies on reaction mechanisms may be performed by the candidate or as part of a collaboration, depending on the scholar’s interests.

The PhD candidate will also participate in the Institute scientific life by attending to group and institute seminars and lectures. The PhD candidate will also attend to advanced course devoted to modern organic chemistry and spectroscopy.

Researcher profile

R1

Number of positions available

1

Offer

Terms of employment: scholarship for 48 months – stipend (including employer’s costs) 5,000 PLN per month (~4200 PLN gross) paid from NSC grant

Benefits: private medical care package, co-financing of sports cards, possibility of accommodation at the Doctoral Hotel

Career development opportunities:

  • work in young and dynamic research group;
  • access to modern research infrastructure of IOC PAS, including NMR, MS;
  • access to modern laboratory equipment, including a glovebox chamber, a microwave synthesizer, mills for mechanochemistry, high-pressure apparatus, flash chromatographs, HPLC chromatographes, GC & GCMS chromatographes, polarimeter.
  • professional development in the field stereoselective organic synthesis
  • opportunity to participate in national and international scientific conferences and workshops;
  • opportunity for further professional development in IOC PAS.

Additional information

Project manager: dr hab. Bartosz Zambroń

Phone: +48 22 343 2141

e-mail: bartosz.zambron@icho.edu.pl

Requirements

A prerequisite for qualifying for the project is the PhD student status at the Warsaw PhD School in Natural and BioMedical Sciences (the interviews will be held from 26 June 2023 to 5 July 2023; the deadline for submitting documents to the doctoral school is June 4th, 2023), details are available on the Warsaw4PhD School website as well as the Institute of Organic Chemistry PAS website.

 

Required competencies

  • MSc degree in chemical science (or related areas) or the expected date of obtaining the master degree before starting work;
  • Very good knowledge in organic chemistry,
  • knowledge of English language at the communicative level, be able to write reports and manuscripts for publication in scientific journals;
  • high motivation and a strong commitment to research, creativity;

Desirable competences

  • experience in synthetic organic chemistry especially in the field of arenes and alkenes chemistry
  • ability of  safe handling of air/water sensitive reactions and reagents, the knowledge on advanced synthetic techniques
  • ability of work with unstable compounds;
  • experience in computational chemistry methods

List of required documents

  • Candidate’s Curriculum Vitae
  • description of scientific achievements including a list of publications, patents, monographs etc., a list of realized/ongoing research projects; a list of received research grants;
  • diplomas and certificates confirming the course studies at the BSc and MSc level, with particular focus on the courses related to organic chemistry, completed courses, completed training, etc.;
  • cover letter;
  • letter of recommendation and references from previous supervisor;
  • consent to the processing of the Candidate’s personal data for the purposes of the competition;

Along with the required documents, please submit a signed consent to the processing of personal data available at: https://www.icho.edu.pl/en/cooperations/career/

Candidate evaluation criteria

  • scientific achievements measured by the quality and quantity of scientific publications, monographs, patents, etc., participation in research projects, receiving the research grants;
  • Candidate’s professional experience in the field of organic chemistry evaluated based on submitted forms and an interview
  • career mobility (research internships, work in industry, change of scientific profile)
  • awards or distinctions
  • opinion about the Candidate contained in the letter of recommendation
  • English language knowledge enabling conducting scientific research

Deadline for submitting applications

2023-06-04 23:59

Competition settlement date

2023-07-16

Envisaged job starting date: 1.10.2023

Submitting applications

Secretariat

Institute of Organic Chemistry of the Polish Academy of Sciences

Kasprzaka 44/52 Street

01-224 Warsaw

Phone: +48 22 631 8788

e-mail: rekrutacja@icho.edu.pl

ATTENTION! In the title of the e-mail, please enter “Recruitment – Bartosz Zambron”

Candidates who are not PhD Students of the Doctoral School must take part in the recruitment process to the Warsaw-4-PhD Doctoral School! Details available here!

Recruitment results are sent to all candidates by e-mail to the address indicated in the application immediately after the selection process is completed. The ranking list is available from the contact person indicated in the announcement and from the Human Resources Department of the Institute of Organic Chemistry of the PAS.

 

 

Additional documents required to be submitted to the HR department: