Laboratory for Analysis of Bioactive Compounds

Analytical offer of the Laboratory for Analysis of Bioactive Compounds

  • Confirmation of the identity and properties of the substance

The Laboratory for Analysis of Bioactive Compounds enables the performance of spectra and analyses with all techniques available in individual laboratories. Tests are carried out in accordance with own or customer-required procedures for the purposes of registration and laboratory documentation. We offer NMR, MS, IR, UV-Vis-NIR, ECD, OR/D, VCD, X-ray measurements as well as elemental analysis. Based on the analytical techniques selected by the client or proposed by us, we can confirm the identity and selected properties of any organic substance.

  • Preparation of comprehensive spectral documentation

The Laboratory for Analysis of Bioactive Compounds offers the service of preparing complete spectral documentation confirming the identity and purity of a chemical substance. Such documentation can be used during drug or chemical substances registration processes. It contains a set of spectra according to the list indicated by the client, along with a report including a description of the methodology and the interpretation of spectral data. The documentation may include NMR spectra, MS spectra with chromatographic purity assessment (GC-MS or LC-MS), UV-Vis and IR spectra, elemental analysis and measurement of rotation. The laboratory has the option of including DSC and XRPD measurements subcontracted to another entity in the documentation.

  • Identification of contaminants in drugs and other substances

The Laboratory for Analysis of Bioactive Compounds carries out analyses to identify contaminants in drugs, cosmetics, plant protection products and other products of the chemical industry based on chromatography techniques coupled with LC-MS and GC-MS high-resolution mass spectrometry. We have many years of experience in identifying structures based on advanced measurement techniques of mass spectrometry, both in the case of substances related to product ingredients and impurities of unknown origin. We perform analyses for samples from each production stage, from the synthesis substrates to the final, packed product.

  • Analysis of the composition of mixtures of organic compounds

The Laboratory for Analysis of Bioactive Compounds performs analyses of the composition of solid and liquid samples in terms of identification and content of organic compounds. After the initial consultation, depending on the purpose and subject of the analysis, the analytical technique is selected individually.

  • Qualitative and quantitative determination of organic compounds in any material

The Laboratory for Analysis of Bioactive Compounds performs qualitative and quantitative determinations of organic compounds in various matrices using LC-MS and GC-MS techniques. We use advanced methods of substance isolation (e.g. SPME) and concentration of samples to enable determination of substances in the range of very low concentrations.

  • Manner of providing services

All services are provided only after a formal order has been received by the Institute, in which the scope of the ordered services has been specified. The document must be signed by a person responsible for finances in a given institution or company, such as: president, director, dean, chief accountant, quaestor, grant manager (please provide the grant number). The original or scan of the order should be sent to the address provided in the contact tab. Procedures can be significantly simplified for regular customers.

In the case of standard spectra and measurements using the selected technique, the order should be accompanied by completed order forms for each sample containing the information necessary for the correct performance of the measurement.

In the case of non-standard measurements and comprehensive analyses, the order should refer to a previously prepared detailed offer. Inquiries should be sent to the contact e-mail address: lasb@icho.edu.pl

  • Order execution time

Standard measurements are performed within 2-3 working days. In the case of more complex analyses or a larger number of samples, the execution time is agreed individually.

  • In order to improve contact between clients and analytical laboratories of the IOC PAS, we present below order forms for performing basic analysis:

dr hab. Wojciech Schilf
head of the Laboratory for Analysis of Bioactive Compounds
22 343 33 18
wojciech.schilf@icho.edu.pl

Nuclear Magnetic Resonance Laboratory

 

Analytical service offer of NMR Laboratory in the Institute of Organic Chemistry PAS

The NMR Laboratory is a part of Laboratory of Bioactive Substances Analysis and is equipped with five spectrometers configured to liquid state measurements.

Spectrometer Varian-Agilent 600 MHz (model vnmrs) in standard condition is equipped  with Auto XID probehead. This probehead has invers configuration which is excellent for all measurements with proton channel signal detection. The BB (broadband) channel of this probe covers spectral range from 31P to 15N (from 242.9 to 60.8 MHz). Now, we can offer to our customers the whole set of NMR measurements: 1D, 2D both homonuclear and  heteronuclear correlation and diffusion experiments. The Auto XID probehead allows to run variable temperature experiments in -100 to 100℃ range. For this instrument we have also the Auto XDB probehead with direct configuration, which is very sensitive for heteronuclear direct measurements. This probe has the same spectral and variable temperature ranges as the Auto XID unit.

Spectrometer Varian-Agilent 500 MHz (model vnmrs). Usually, this instrument has installed the Auto XDB direct configuration probehead, which is recommended for direct (signal detection in BB channel) heteronuclear experiments. The variable temperature unit allows to achieve  the -100 to 100℃ temperature range. The high frequency channel of this probehead can be used for fluorine spectra measurements. The BB channel covers spectral range from 31P to 15N (from 202.4 to 50.7 MHz). This probehead can be used also for invers correlation measurements, but it is not recommended because of significantly lower sensitivity of proton channel detection, comparing with Auto XID unit.

Spectrometer Bruker 500 MHz (model DRX Avance). This instrument has installed the TBI probehead in invers configuration, which was optimized for signal detection in proton channel. In contrast to Varian-Agilent spectrometers the TBI probe can be used for measurements in spectral range from 31P to 109Ag (from 202.4 to 23.3 MHz). The variable temperature unit of the Bruker 500 spectrometer is working in the range of -60 to 80℃. In this hardware configuration Bruker instrument can measure all 1D, 2D homo and heteronuclear experiments.

Spectrometer Bruker 400 (Avance III HD). This instrument is equipped with one universal probehead, which allows to measure both: experiments with proton (invers type) and BB channel (direct type) detection, without significant loss of sensitivity, comparing with dedicated probes. The broad band (BB) channel in this probe covers the spectral range from 19F to 109Ag (from 376.5 to 18.6 MHz), which provides possibility to acquire 1H – 19F correlations. The Bruker 400 instrument has the variable temperature facility working in -80 to 60℃ range without any cryogenic liquids and without any hardware reconfigurations.

Spectrometer Varian 200 MHz (Gemini). In current configuration this instrument can measure only proton and carbon spectra. The probehead used (direct configuration) is suitable for 1D 1H and 13C spectra and for some simply heteronuclear correlation. The more challenging correlation are not recommended on this spectrometer, because of relatively low sensitivity, comparing with the other machines in our Laboratory. Only room temperature measurements are accessible on this spectrometer.

All our spectrometers are connected to the internet system of the Institute and it is possible to transfer experiment results to user computers for data processing. Because of this we can use our instruments only for data acquisition, which make our work more efficient.

Varian-Agilent and Bruker 500 spectrometers are operated by our experienced operators, which can keep very high quality measurement level. All experiments are performed on the base of Measurement Order Form supplied together with the sample to the NMR Laboratory and results are saved on our server, where they are available for the customers. On request, we can supply the paper version of the spectra.

The two remaining spectrometers: Bruker 400 and Varian 200, are assigned to self-service operation. To operate this machines a short training and examination for new users are necessary. Both self-service spectrometers are available seven days a week, 24 hours a day.

dr hab. Wojciech Schilf
head of laboratory
22 343 33 18
wojciech.schilf@icho.edu.pl

dr Marta Bugaj-Zarębska
22 343 20 14
marta.bugaj@icho.edu.pl

dr Piotr Cmoch
22 343 25 52
piotr.cmoch@icho.edu.pl

dr Bohdan Kamieński
22 343 20 03
bohdan.kamienski@icho.edu.pl

mgr inż. Jerzy Sitkowski
22 343 25 52
jerzy.sitkowski@icho.edu.pl

dr Olga Staszewska-Krajewska
22 343 25 52
olga.staszewska@icho.edu.pl

mgr inż. Anna Tabaszewska
22 343 25 52
anna.tabaszewska@icho.edu.pl

mgr Kamila Stępień
22 343 20 14
kamila.stepien@icho.edu.pl

Nuclear Magnetic Resonance Laboratory

measurement on a spectrometer: price for non-commercial clients price for commercial clients
600 MHz 120 PLN/hour. 140 PLN/hour.
500 MHz 100 PLN/hour. 110 PLN/hour.
400 MHz 50 PLN/hour.
200 MHz 35 PLN/hour.

For samples dissolved in CDCl3, DMSO-d6, D2O, benzene-d6 and acetone-d6, the cost of the solvent used is included in the price of the spectrum. For the remaining samples, the cost of the solvent used will be added to the price of the spectra in accordance with the following price list:

solvent price
acetonitrile-d3 9,30 PLN
dimethylformamide-d7 74,20 PLN
methanol-d4 13,80 PLN
dichloromethane-d2 14,00 PLN
pyridine-d5 13,90 PLN
toluene-d8 10,70 PLN
trifluoroacetic acid-d 12,20 PLN

The costs of other, non-standard solvents will be calculated based on the supplier’s current price lists.

Mass Spectrometry Laboratory

 

Mass Spectrometry Laboratory of the Institute of Organic Chemistry PAS for more than 20 years is delivering a high quality service in all branches of organic mass spectrometry. Cooperation with the synthetic organic chemistry research groups in our Institute, as well as large number of customers from other academic and industrial institutions resulted in thousands of samples per year our lab had to measure. The experience we gathered during this work allowed us to perform practically all types of MS analyses for organic compounds.

Presently we have 6 spectrometers which offer the following ionization methods: EI, CI, ESI, APCI, APPI, MALDI, FD and FI. All measurements can be performed in low resolution and high resolution modes. We offer also GC-MS (together with identification of known compounds using NIST and Wiley databases) and HPLC-MS (also UPLC-MS) analyses. Our specialty are structural studies using MS/MS and MS3 fragmentation spectra, together with accurate mass measurements.

AutoSpec Premier (Waters) coupled with HP 7890 (Agilent) gas chromatograph with advanced autosampler

AutoSpec Premier is a double-focusing magnetic sector instrument with EBE geometry. Solid and non-volatile liquid samples can be introduced via a heated direct insertion probe. Volatile samples can be introduced via CG or heated reference inlet chamber. The entire system is controlled and data are processed using MassLynx software.

We are using AutoSpec Premier spectrometer for the following measurements:

  • standard low resolution EI and CI mass spectra,
  • accurate mass measurements with an average error below 2 ppm,
  • MIKE, B/E, B2/E and CNL for metastable ions as well as in CID mode.

Basic parameters of the AutoSpecspectrometer:

  • mass range: 2 000 m/z at full acceleration voltage (8 kV),
  • resolving power up to 80 000,
  • EI and CI ion sources,
  • collision chambers in the first and the third field free regions.

MaldiSYNAPT G2-S HDMS (Waters) coupled with ACQUITY UPLC I-Class System (Waters) ultra-performance liquid chromatography system.

Maldi SYNAPT G2-S HDMS spectrometer is the top model of the Waters QTOF-type machines. This is a hybrid QqTOF spectrometer with very sophisticated, three-part collision chamber. Central part of this chamber is used for the Ion Mobility Mass Spectrometry (IM-MS) technique. This unique method is based on the measurement of the drift times of ions in the chamber filled with collision gas. Drift times are then converted into collisional crossection values which can be related to the shape of the molecule. This makes possible distinguishing isomers and conformational studies in the gas phase. Time of flight mass analyzer makes possible accurate mass measurements for the ions and establishing their molecular formula with highcertainty. SYNAPT mass spectrometer can be coupled with UPLC Acquity (Waters) ultra-performance liquid chromatograph. SYNAPT is used for accurate mass measurements of pure samples and the samples separated by UPLC (accuracy better than 2 ppm) and for structural studies using collisional induced dissociation (CID) and ion mobility methods.

Basic parameters of the SYNAPT spectrometer:

  • ESI, APCI, APPI, MALDI, ASAP (AtmosphericSolids Analysis Probe)
  • mass range: 40 – 8000 m/z
  • resolvingpower: up to 40 000

GCT Premier (Waters) + Agilent 6890N gas chromatograph

GCT Premiermass spectrometer is based on the time of flight (TOF) mass analyzer so it offers high resolution measurements. This instrument is equipped with four exchangeable ion sources: EI (Electron Ionization), CI (Chemical Ionization), FD (Field Desorption) and FI (Field Ionization – only in connection with gas chromatograph). Samples can be introduced via Agilent 6890N gas chromatograph (EI, CI and FI modes) or via FD probe. GCT Premier is used mainly for high and low resolution FD spectra measurements and for GC-MS analyses when accurate mass measurements are required.

Basic parameters of the GCT Premier are:

  • mass range: 4000 m/z
  • resolving power: >7000

4000 Q-TRAP (Applied Biosystems, presently AB SCIEX) + Prominence (Shimadzu) liquid chromatograph

Mass spectra on the 4000 Q-TRAP mass spectrometer can be recorded using three ionization methods: ESI (Electrospray Ionization), APCI (Atmospheric Pressure Chemical Ionization) and APPI (Atmospheric Pressure Photoionization, Photospray). 4000 Q-TRAP is a triple quadrupole-type instrument with a linear ion trap in place of the third quadrupole. This configuration makes possible all kinds of measurements which can be done using ‘classical’ triple quad with addition of some special experiments like MS3 double-stage fragmentation and measurements in enhanced resolution or sensitivity modes. This machine works perfectly with HPLC chromatograph making possible analyses of very complex mixtures. In our lab 4000 Q-TRAP is coupled with Shimadzu Prominence (LC-20) HPLC system. We offer a broad range of chromatographic columns. We can help also in designing optimal conditions (column, eluent) HPLC analysis conditions. 4000 Q-TRAP mass spectrometer is used mainly for HPLC-MS analyses, standard low resolution spectra measurements in ESI, APCI and APPI modes and for analyses within the frame of the Laboratory for the Analyses of Bioactive Compounds.

Basic parameters of 4000 Q-TRAP mass spectrometer:

  • mass range: 5 – 2800 m/z
  • scanning rates up to 4000 Da/s
  • resolving power> 3000

API 3000 (Applied Biosystems, presently SCIEX)

API 3000 is ‘classical’ triple-quadrupole mass spectrometers equipped with ESI (Electrospray Ionization) and APCI (Atmospheric Pressure Chemical Ionization) ion sources. It can be used for measurement of the standard low resolution spectra, a s well as for MS/MS experiments. Spectrometer is used mainly for recording low resolution spectra in ESI and APCI modes. The mass range of spectrometer is 3000 m/z with unit resolution.

Agilent 7890A & 5975CGC/MS system

The system consists of the Agilent 7890A gas chromatograph coupled with Agilent 5975C single quadrupole mass spectrometer with EI and CI ion sources. Gas chromatograph is equipped with an autosampler for 100 vials. Additionaly, samples can be introduced through the Headspace autosapmpler. Recorded spectra can be compared with NIST 08 mass spectral library. This system is used for routine GC/MS analyses.

Basic parameters:

  • mass range: up to 1050 m/z
  • max. oven temperature: 450 °C

dr Dorota Staszek
head of laboratory
22 343 22 19
dorota.staszek@icho.edu.pl

mgr Ewa Gruba
22 343 22 11
ewa.gruba@icho.edu.pl

mgr inż. Klara Nestorowicz
22 343 22 11
klara.nestorowicz@icho.edu.pl

mgr inż. Marian Olejnik
22 343 22 09
22 343 22 11

marian.olejnik@icho.edu.pl

mgr Aleksandra Zasada
aleksandra.zasada@icho.edu.pl

Mass Spectrometry

measurement on a spectrometer: price for non-commercial clients price for commercial clients
EI measurement – low resolution spectrum (EI-LR) 80 PLN/sample 110 PLN/sample
EI measurement – low and high resolution spectrum (EI-LR+HR) 140 PLN/sample 190 PLN/sample
ESI measurement – low resolution spectrum (ESI-LR) 110 PLN/sample 140 PLN/sample
ESI measurement – high resolution spectrum (ESI-HR) 200 PLN/sample 240 PLN/sample
APPI and APCI measurement – low resolution spectrum (APPI-LR and APCI-LR) 110 PLN/sample 140 PLN/sample
APPI and APCI measurement – high resolution spectrum (APPI-HR and APCI-HR) 200 PLN/sample 240 PLN/sample
ASAP measurement – high resolution spectrum (ASAP-HR) 110 PLN/sample 140 PLN/sample

Laboratory of Optical Spectroscopy

 

Laboratory of Optical Spectroscopy of the Institute of Organic Chemistry (Polish Academy of Sciences) for over 30 years has been dealing with measurements of organic compounds. Our unique blend of expertise and resources enables us to perform various chemical compounds professionally using the newest instruments for optical and chiroptical spectroscopies. We also help in matters related to selection of appropriate measurement methods/techniques.

UV-VIS-NIR spectroscopy encompasses the ultraviolet, visible and near-infrared region of the electromagnetic spectrum. This technique is routinely used for the qualitative and quantitative analysis of any chemical compounds containing in their structure chromophoric system.
Specialized equipment of the Laboratory of Optical Spectroscopy allows to analyze various samples in the range from 190 nm to 2700 nm using both the transmission and reflected methodologies, in solution and in solid phase.

Analytical capabilities

  • qualitative and quantitative measurements in solution and solid-state;
  • kinetics and temperature UV-VIS-NIR spectra.

Equipment

  • Spectrophotometer UV-VIS-NIR Jasco V-670;
  • Spectrophotometer UV-VIS Carry 100E.

IR spectroscopy allows analyzing the structure of molecules (and detect functional groups) and their interaction with the environment.
The Laboratory of Optical Spectroscopy carries out analytical services in the advanced generation of FTIR spectrometers and sampling accessories to analyze solids and liquids using transmission and reflectance (ATR) techniques.

Analytical capabilities

  • IR measurements using transmission methods;
  • IR measurements using ATR accessory (with diamond or ZnSe crystal);
  • kinetics IR spectra.

Equipment

  • Spectrophotometer FTIR Jasco 6200;
  • Spectrophotometer FTIR Shimadzu IR Tracer-100.

Electronic Circular Dichroism spectroscopy is a widely used method for determining the absolute structure of molecules in solution and solid-phase. It is a rapid, sensitive and reliable technique for determining 3D structure (not only configuration but also conformation), provided that the substance is chiral, non-racemic, and absorbs circularly polarized light in the available spectral range (180 – 1100 nm).
The Laboratory of Optical Spectroscopy is equipped with two modern ECD spectrometers with an extensive range of accessories and attachments that record the high-quality spectra for a wide range of chiral compounds. We also offer assistance in selecting appropriate chiroptical methods (ECD/ORD/VCD) to solve specific stereochemical problems appearing in the structural analysis of chiral compounds.

Analytical capabilities

  • ECD measurements in solution and solid state;
  • ECD temperature-dependent measurements within the range from +250 °C to -196 °C;
  • ECD kinetics measurements;
  • linear dichroism measurements (LD);
  • measurements of protein with estimation of the secondary structure;
  • HPLC separations with ECD detection with the possibility of recording a full ECD spectrum.

Equipment

  • Spectropolarimeter ECD Jasco J-715;
  • Spectropolarimeter ECD Jasco J-815, for solid state measurements;
  • Peltier Cell Holder;
  • Solid-state accessory for DTCD/DRCD;
  • Automatic Titrator;
  • Cryostat Optistat, Oxford Instruments;
  • Thermostat Specac;
  • Analytical HPLC set with typical chiral columns.

ORD spectroscopy is a technique complementary to the ECD, and it records the variation of optical rotation of chiral substances as a function of the wavelength of linearly polarized light. ORD spectroscopy is used in the analysis of optically active compounds, including no-absorbing systems. The application of ORD spectroscopy will facilitate stereochemical analysis of many chiral compounds that exhibit low values of specific rotation at 589 nm.

Analytical capabilities

  • OR measurements at a selected wavelength(s) (standard 589 nm, other possibilities: 578, 546, 436, 405, 365 nm) at the constant temperature;
  • ORD measurements in the range 200 – 850 nm at the constant temperature;
  • variable temperature ORD measurements;
  • kinetics ORD measurements.

Equipment

  • Digital Polarimeter, Jasco P-2000;
  • Spectropolarimeter ORD Jasco J-815;
  • Peltier Cell Holder.

VCD spectrometer records the chiroptical spectra in the IR range. VCD can be regarded as an extension of ECD to the IR range, where the oscillatory transitions occur only within the ground-state of the molecule. The range of applications of VCD for structural studies of chiral substances is large. It is due to no need to have a chromophore in the molecule.
The Laboratory of Optical Spectroscopy is equipped with the latest generation of VCD spectrometer with the spectral range 4000 – 850 cm-1. The introduction of Dual Source and Dual PEM technology to VCD spectroscopy has opened new possibilities for the analysis of samples in the solid phase.

Analytical capabilities

  • VCD measurements in solution and in solid-state;
  • Temperature-dependent measurements.

Equipment

  • ChiralIR-2XTM DualPEM BioTools spectrometer;
  • Thermostat Specac.

dr Marcin Górecki
head of laboratory
22 343 22 12
marcin.gorecki@icho.edu.pl

dr Anna Kamińska
22 343 22 12
anna.kaminska@icho.edu.pl

Alicja Dziedzic
22 343 22 14
alicja.dziedzic@icho.edu.pl

Ewa Zawistowska
22 343 22 14
ewa.zawistowska@icho.edu.pl

Optical Spectroscopy

price for non-commercial clients price for commercial clients
IR spectrum 60 PLN/sample 80 PLN/sample
VCD spectrum 50 PLN/hour 70 PLN/hour
UV-VIS-NIR spectrum 80 PLN/hour 100 PLN/hour
ECD spectrum 100 PLN/hour 120 PLN/hour
Temperature-dependent ECD measurements (Peltier Cell Holder; Cryostat Optistat) 120 PLN/hour 140 PLN/hour
HPLC analysis 100 PLN/hour 120 PLN/hour
HPLC-ECD analysis 160 PLN/hour 180 PLN/hour
ORD spectrum 120 PLN/hour 140 PLN/hour
Others types of measurements price negotiable individually price negotiable individually

Laboratory of X-ray Structural Analysis

The X-Ray Diffraction Laboratory is equipped with modern Bruker AXS diffractometer with area detektor APEX II which allows for advanced X-ray diffraction characterization of monocrystalline organic and metalloorganic materials. Application of Cu-radiation is particularly useful in studies of small to medium size (10-500 atoms) organic molecules, including assignement of absolute configuration.
Low temperature device designed by Oxford Cryosystems provides opportunity to study structure and phase transitions in the 100 – 373 K temperature range.

Another availavle option is possibility of measurement of crystal size and face indexing that makes sit useful for some solid phase physiscs.

Optical microscope Nikon Eclipse E200 along with Linkam THMS 600 hot stage (up to 350 oC) and camera provides tolls for observation and registration of samples under the polarized light, following phase transition, growth of polymorphs, etc.

dr Marcin Górecki
head of laboratory

48 22 343 22 12
marcin.gorecki@icho.edu.pl

dr Maja Morawiak
22 343 22 07
maja.morawiak@icho.edu.pl

X-ray Structural Analysis

price for non-commercial clients price for commercial clients
Measurement without calculations 600 PLN/sample 800 PLN/sample
Measurement and calculations 1400 PLN/sample 1600 PLN/sample
Nitrogen for measurement at low temperature 50 PLN/ 60 l N2 50 PLN/ 60 l N2

Laboratory of Elementary Analysis

The Laboratory of Elementary Analysis is one of the oldest analytical laboratory at the IOC PAS. From the beginning of the Laboratory to the present days, we pride ourselves on the possibility of working on top-class devices, thanks to which we obtain precise results.

The analysis of the percentage of C, H, N, S content is performed in an automatic UNIcube analyzer by Elementarcompany. The basis of the measurement is the catalytic combustion of the analyzed substance at 1150 °C in the oxygen atmosphere. After cleaning of interfering gases (e.g. volatile chlorides), the combustion gases are separated on adsorption columns and determined successively by a thermal conductivity detector (TCD).

The analysis of the percentage of halogens and sulfuris determined mainly using the Schőniger method. After mineralization of the analyzed sample on the platinum catalyst in the flask filled with oxygen, the resulting ions are determined by titration:

  • F – Schöniger method; titration with Th(NO3)4• 5H2Osolution
  • Br – Schöniger method; titration with Hg(ClO4)2 solution
  • S – Schöniger method; titration with Ba(ClO4)2 solution.
  • Cl, I – potentiometric-argentometric method; titration with AgNO3 solution

At the customer’s request, we also carry out precise weights of small amounts of substances.

mgr Krystyna Markucińska
head of laboratory
22 343 20 04
krystyna.markucinska@icho.edu.pl

mgr Ewa Czykiel
22 343 20 04
ewa.czykiel@icho.edu.pl

Katarzyna Gwardiak
22 343 20 04
katarzyna.gwardiak@icho.edu.pl

Elementary Analysis

price for non-commercial clients price for commercial clients
CH content 130 PLN/sample 140 PLN/sample
N content 65 PLN/sample 70 PLN/sample
XS content 65 PLN/sample 70 PLN/sample

Preparation of the analytical weight

10 PLN/sample 10 PLN/sample

Comprehensive Analysis Laboratory

Detailed information on comprehensive services provided by the Comprehensive Analysis Laboratory, including consultations on the selection of appropriate measurement methods and techniques, preparation of offers, preparation of reports are provided by:

dr Beata Naumczuk
22 343 22 19
beata.naumczuk@icho.edu.pl
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Order forms

In order to improve contact between clients and analytical laboratories of the IOC PAS, we present below order forms for performing basic analysis: