Head of the group
Assoc. Prof. Rafał Loska

Professors
Prof. Mieczysław Mąkosza

Assistants
Dr Anjali

PhD Students
M.Sc. Jakub Brześkiewicz
M.Sc. Barbara Stańska
M.Sc. Mastan Sharief Syed
M.Sc. Alicja Wasilewska-Rosa

Chemists
Małgorzata Pawlak-Bechcicka

OPUS NCN 2022/47/B/ST4/01498
Palladium-catalyzed cascades for the rapid and enantioselective construction of polycyclic scaffolds of alkaloids and pseudo-natural products”

Publications

J. Brześkiewicz, R. Loska, „Construction of Nitrogen Spirocycles in a Tandem Co(III)-catalyzed C–H Activation/Dipolar Cycloaddition Reaction”, Advanced Synthesis & Catalysis

M. Barbasiewicz, M. Fedoryński, R. Loska and M. Mąkosza, „Analogy of the Reactions of Aromatic and Aliphatic π-Electrophiles with Nucleophiles”, Molecules

A. Wasilewska-Rosa, K. Kisiel, A. Tkaczyk, R. Loska, „Stereospecific Synthesis of Allenes from beta-Ketosulfones”, Adv. Synth. Catal.

J. Brześkiewicz, R. Loska, „Synthesis of Isoindole N-Oxides by Palladium-Catalyzed C–H Functionalization of Aldonitrones”, J. Org. Chem.

A. Zasada, J. Brześkiewicz, D. Antoniak, M. Bechcicka, R. Loska, M. Mąkosza, „Synthesis of Quinoxaline Derivatives via Aromatic Nucleophilic Substitution of Hydrogen”, Org. Biomol. Chem.

J. Brześkiewicz, B. Stańska, P. Dąbrowski, R. Loska, „C−H Activation and Cross‐Coupling of Acyclic Aldonitrone”, Eur. J. Org. Chem.

M. Sacha, M. Błaż, P. Byrski, P. Dąbrowski-Tumański, M. Chromiński, R. Loska, P. Włodarczyk-Pruszyński, S. Jastrzębski, „Molecule Edit Graph Attention Network: Modeling Chemical Reactions as Sequences of Graph Edits”, J. Chem. Inf. Model.

M. Mąkosza, „Does Nucleophilic Substitution in Nitroarenes Proceed via Single Electron Transfer (SET)?”Eur. J. Org.Chem.

M. Mąkosza, M. Bechcicka, K. Wojciechowski, „Simple Synthesis of Dimethyl Nitrobenzhydrylphosphonates and Heteroarylnitroarylacetonitriles via Vicarious Nucleophilic Substitution (VNS) Reaction”, Synthesis

M. Mąkosza, M. Fedoryński, „Dichlorocarbene and analogs: discovery, properties and reactions”, Russ. Chem. Bull.

K. Kisiel, J. Brześkiewicz, R. Loska, M. Mąkosza, „Transition Metal Free Nucleophilic Benzylation of Nitroarenes. Umpolung of the Friedel Crafts Reaction”, Adv. Synth. Catal.

P. Bukowska, J. Piechowska, R. Loska, „Azine-imidazole aza-BODIPY analogues with large Stokes shift”, Dyes and Pigments

R. Loska, „Recent Advances in Cycloaddition Reactions of Heterocyclic N-Oxides”, Topics in Heterocyclic Chemistry, O. Larionov (ed.)

Research topics

  • Transition metal-catalyzed C–H activation of nitrones
  • Allene synthesis
  • New variants of Nucleophilic Substitution of hydrogen in aromatic systems