Head of the group
Prof. Bartłomiej Furman

Professors
Prof. Marek Chmielewski

Adjuncts
Dr. Piotr Szcześniak

Assistants
Dr. eng. Paweł Czerwiński
Dr Supratim Chakraborty

Chemists
Dr. Barbara Grzeszczyk

PhD students
M.Sc. eng. Justyna Najczuk
M.Sc. Magdalena Dolna

NCN Sonata 2019/35/D/ST4/00028 „Photochemical rearrangement of lactams: A ring-expansion approach towards structurally diverse heterocycles”

NCN OPUS (2019/35/B/ST4/02794) „Synthesis of structurally diverse medium- and large-sized rings by controlled decomposition of tetraoxanes and related compounds”

Publications

M. Chmielewski, R. Kutaszewicz, A. Ulikowski, M. Michalak, K. Wołosewicz, S. Stecko, B. Furman, „The Kinugasa Reaction”, Organic Reactions

M. M. Więcław, B. Furman, Direct synthesis of anomeric tetrazolyl iminosugars from sugar-derived lactams, Beilstein J. Org. Chem.

P. Szcześniak, B. Grzeszczyk, B. Furman, „A Convenient Approach towards the Synthesis of ADMDP Type Iminosugars and Nojirimycin Derivatives from Sugar-Derived Lactams”, Molecules

P. Szcześniak, B. Furman, „Concise synthesis of bicyclic iminosugars via reductive functionalization of sugar-derived lactams and subsequent RCM reaction”, Org. Biomol. Chem.

P. Czerwiński, B. Furman, „Reductive Functionalization of Amides in Synthesis and for Modification of Bioactive Compounds”Front. Chem.

O. Gawryś, M. Rak, I. Baranowska, S. Bobis-Wozowicz, K. Szaro, Z. Madeja, E. Kula-Świeżewska, M. Masnyk, M. Chmielewski, E. Karnas, E. Kompanowska-Jezierska, „Polyprenol-Based Lipofecting Agents for In Vivo Delivery of Therapeutic DNA to Treat Hypertensive Rats”, Biochem. Genet.

K. Kabala, B. Grzeszczyk, B. Furman, M. Chmielewski, J. Solecka, A. Guśpiel, „Synthesis of Monobactams via the Diastereoselective Kinugasa Reaction”, Synthesis

B. Szechner, A. Jaromin, S. Parapini, N. Basilico, B. Grzeszczyk, B. Furman, M. Chmielewski, „Glycosyl hydroperoxides: A new class of potential antimalarial agents”, Bioorg. Med. Chem.

P. Plata, U. Klimczak, B. Zambroń, ”Acyclic Remote 1,5- and 1,4,5-Stereocontrol in the Catalytic Stereoselective Reactions of β-Lactams with Aldehydes: The Effect of the N-Methylimidazole Ligand”, J. Org. Chem.

P. Szcześniak, O. Staszewska-Krajewska, B. Furman, J. Młynarski, „Solid supported Hayashi–Jørgensen catalyst as an efficient and recyclable organocatalyst for asymmetric Michael addition reactions”, Tetrahedron: Asymmetry

A. Domżalska, E. Maziarz, B. Furman, „A new synthesis of highly functionalized cyclohexenes via a vinylogous Ferrier-Petasis cyclization reaction”, Tetrahedron

M. Pieczykolan, B. Furman, M. Chmielewski, „Formal synthesis of Thienamycin”, J. Antibiot.

P. Szcześniak, O. Staszewska-Krajewska, B. Furman, J. Młynarski, „Asymmetric Synthesis of Cyclic Nitrones via Organocatalytic Michael Addition of Aldehydes to Nitroolefins and Subsequent Reductive Cyclization”, Chemistry Select

G. Lipner, A. Ulikowski, A. Domżalska, B. Furman, „Flexible synthesis of fused piperidinones and application in the synthesis of (+/-)-myrtine”, Tetrahedron

M. Pieczykolan, O. Staszewska-Krajewska, B. Furman, M. Chmielewski, „1,3-Dipolar cycloaddition of a cyclic nitrone derived from 2-deoxy-D-ribose to alpha,beta-unsaturated lactones: An entry to carbapenem antibiotics”, Carbohydr. Res.

P. Szcześniak, A. Ulikowski, O. Staszewska-Krajewska, G. Lipner, B. Furman, „Stereoselective synthesis of benzoquinolizidines and related homologues via intramolecular addition to dihydropyridones”, Tetrahedron

K. Wolosewicz, M. Michalak, J. Adamek, B. Furman, “Studies on the Enantioselective Kinugasa Reaction: Efficient Synthesis of beta-Lactams Catalyzed by N-PINAP/CuX Complexes”, Eur. J. Org. Chem.

M. Soluch, B. Grzeszczyk, O. Staszewska-Krajewska, M. Chmielewski, B. Furman, „Synthesis of Thienamycin methyl ester from 2-deoxy-D-ribose via Kinugasa reaction”, J. Antibiot.

A. Ulikowski, B. Furman, „Schwartz’s Reagent-Mediated Regiospecific Synthesis of 2,3-Disubstituted Indoles from Isatins”, Org. Lett.

L. Mucha, K. Parda, O. Staszewska-Krajewska, S. Stecko, A. Ulikowski, J. Frelek, A. Suszczyńska, M. Chmielewski, B. Furman, „Diastereoselective synthesis of beta-lactams via Kinugasa reaction of acyclic chiral nitrones”, Tetrahedron: Asymmetry

RESEARCH TOPICS

  • Chemoselective activation of amide carbonyls towards nucleophilic reagents
  • Kinugasa Reaction as a Stereoselective Method of β-Lactams Synthesis: Advanced Applications
  • Studies on the rearrangement of vinyl ethers and alkoxydienes
  • Reactions of functionalized organometallic compounds
  • Tesliper software to improve the process of simulating optical spectra