Head of the group
Prof. Agnieszka Szumna

Assistants
Dr Hanna Jędrzejewska
Dr Arturo llamosi Fornes
Dr Esma Abdurakhmanova

PhD Students
Mgr inż. Marek Szymański
Mgr inż. Arkadiusz Sakowicz
Mgr Monika Chwastek
Mgr Agnieszka Głowacka
Mgr Paulina Jurek

HORYZONT 2020 H2020-MSCA-ITN-2017 765297-NOAH
“Network of Functional Molecular Containers with Controlled Switchable Abilities”

NCN OPUS 2021/41/B/ST4/01650
„Mechanochemical self-assembly of anion-sealed molecular capsules”

NCN SYMFONIA 2016/20/W/ST5/00478
„Supramolecular Peptide Organic Frameworks (POFs)”

416495/PnH/2018
„Network of Functional Molecular Containers with Controlled Switchable Abilities”

NAWA Bilateral exchange of scientists between the Republic of Poland and the Czech Republic PPN/BIL/2018/1/00063/U/00001
„Enkapsulacja potencjalnych leków na bazie kompleksów matali w kapsułach supramolekularnych ”

Wroclaw Centre for Networking and Supercomputing (299)
“Ab inito calculations of chiroptical properties of inherently chiral molecules”

Publications

M. Chwastek, P. Cmoch, A. Szumna, „Dodecameric Anion‐Sealed Capsules based on Pyrogallol[5]arenes and Resorcin[5]arenes”, Angew. Chem. Int. Ed.

R. Orłowski, J. A. Clark, J. B. Derr, E. M. Espinoza, M. F. Mayther, O. Staszewska-Krajewska, J. R. Winkler, H. Jędrzejewska, A. Szumna, H. B. Gray, V. I. Vullev, D. T. Gryko, “Role of intramolecular hydrogen bonds in promoting electron flow through amino acid and oligopeptide conjugates”, Proc. Nat. Acad. Sci. U. S. A.

M. Szymański, M. Grajda, A. Szumna, „Amplification of Electronic Circular Dichroism—A Tool to Follow Self-Assembly of Chiral Molecular Capsules”, Molecules

M. Gilski, P. Bernatowicz, A. Sakowicz, M. P. Szymański , A. Zalewska , A. Szumna, M. Jaskólski, „C60 in a peptidic cage: a case of symmetry mismatch studied by crystallography and solid-state NMR”, Acta. Cryst. B. Struct. Sci. Cryst. Eng. Mater.

S. J. Nemat, H. Jędrzejewska, A. Prescimone, A. Szumna, K. Tiefenbacher, „Catechol[4]arene: The Missing Chiral Member of the Calix[4]arene Family”, Org. Lett.

M. Chwastek, A. Szumna, „Higher Analogues of Resorcinarenes and Pyrogallolarenes: Bricks for Supramolecular Chemistry”, Org. Lett.

A. Szafraniec, M. Grajda, H. Jędrzejewska, A. Szumna, W. Iwanek, „Enaminone Substituted Resorcin[4]arene—Sealing of an Upper-Rim with a Directional System of Hydrogen-Bonds”, Int. J. Mol. Sci.

H. Jędrzejewska, E. Wielgus, S. Kaźmierski, H. Rogala, M. Wierzbicki, A. Wróblewska, T. Pawlak, M. J. Potrzebowski, A. Szumna, „Porous Molecular Capsules as Non‐Polymeric Transducers of Mechanical Forces to Mechanophores”, Chem. Eur. J.

M. P. Szymański, J. S. Czajka, P. Cmoch, W. Iwanek, A. Szumna, „Interlaced capsules by self-assembly of cavitands substituted with tripeptides and tetrapeptides”, Supramol. Chem.

S. Kosiorek, B. Rosa, T. Boinski, H. Butkiewicz, M. P. Szymański, O. Danylyuk, A. Szumna, V. Sashuk, „Pillar[4]pyridinium: a square-shaped molecular box”, Chem. Commun.

M. Grajda, M. J. Lewińska and A. Szumna, „The templation effect as a driving force for the self-assembly of hydrogen-bonded peptidic capsules in competitive media”, Org. Biomol. Chem.

M. P. Szymański, H. Jędrzejewska, M. Wierzbicki, A. Szumna, „On the mechanism of mechanochemical molecular encapsulation in peptidic capsules”, Phys. Chem. Chem. Phys.

M. Wierzbicki, A. A. Głowacka, M. P. Szymański, A. Szumna, J.„A chiral member of the family of organic hexameric cages”, Chem. Commun.

T. Boinski, A. Szumna, „Hybrid[4]arenes with anthracene units and tuneable cavities”, New J. Chem.

H. Jędrzejewska, A. Szumna, „Making a Right or Left Choice: Chiral Self-Sorting as a Tool for the Formation of Discrete Complex Structures”, Chem. Rev.

Research topics

  • peptidic cavitands and supramolecular capsules, their complexation abilities, chiral recognition
    (We synthesize chiral cavitands of various properties using amino acids derivatives and short peptides.)
  • cavitands with core-extended chromophores, photophysical properties of host-guest complexes
  • multicomponent molecular capsules, host-guest interactions, reactions inside molecular containers
    (Introduction of various functional groups to the macrocyclic scaffolds and other building blocks enables synthesis of capsules with functionalized interior.)
  • interactions of macrocyclic compounds with proteins in solution and solid state (co-crystallization)
    (Association of small compounds with proteins and self-organisation of proteins in COFs facilitate crystallization of the latter.)
  • mechanochemistry of molecular containers and host-guest complexes
    (Mechanochemical methods can change complexing properties.)
  • new macrocyclic compounds
    (We synthesize new supramolecular scaffolds with new shapes and/or new binding properties.)