In the article, the authors examine, among others dependence of the quantity of discovered chemical compounds on the number of types of reactions (old, well-known and new, more complicated ones) as a function of time, popularity of the reaction type and their complexity based on an algorithm extracting generalized patterns of reaction classes. These analyses are useful in the context of computer-assisted synthesis, machine learning, and also for identifying erroneous entries in reaction databases.
The publication of Prof. Bartosz Grzybowski: https://onlinelibrary.wiley.com/doi/10.1002/anie.202111540
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