Laboratory for Analysis of Bioactive Compounds

A. Gumieniczek, D. Buś, E. Oleszek, B. Naumczuk, P. Hołowiński, „Comprehensive Analytical Investigation of the Photodegradation of Olopatadine and In Silico Toxicity Assessment of Its Photodegradation Products”, Molecules

A. Leśniewska, A. Buczkowski, P. Ruszkowski, M. J. Binder, A. D. Axtman, W. Schilf, E. Smolarz, K. Pyta, M. Gdaniec, F. J. Bartl, P. Przybylski, „Cascade Mono- and Di-Functionalization of Anticancer Diastereomeric Benzoxazole-Ansamycins toward the Development of Highly Potent Hsp90 Inhibitors of Decreased Toxicity in Normal Cells”, J. Med. Chem.

J. Hetmańczyk, Ł. Hetmańczyk, J. Nowicka-Scheibe, M. Morawiak, W. Schilf, A. Pawlukojć, „Structure and vibrational spectra of hydrogen-bonded complexes of squaric acid with 2,4- and 3,5-lutidine”, J. Mol. Struct.

B. Hashemi Hosseini, D. Łomot, B. Naumczuk, A. Dyachenko, M. Krawczyk, J. Carlos Colmenares, „Metal-Free Sonophotocatalytic C─C Coupling of Acetovanillone Using a Synthesis-Frequency-Tuned Chitosan–Lignin Hybrid Catalyst”, Chem. Eur. J.

M. Paszkiewicz-Gawron, P. Martinez-Marco, D. Łomot, B. Naumczuk, B. Hashemi Hosseini, J. Carlos Colmenares, „Sonophotocatalytic dimerization of coniferyl alcohol – The influence of energy distribution during sonication”, Ultrasonics Sonochemistry

P. Surynt, B. Naumczuk, M. Popławska, M. Urbanowicz, K. Unrug-Bielawska, M. Cybulska-Lubak, Z. Sadowska-Markiewicz, J. Sitkowski, E. Bednarek, N. Zeber-Lubecka, L. Kozerski, M. Mikula, J. Ostrowski, „Metabolomic Study of 7-Ethyl-9-(N-methyl)aminomethyl-10-hydroxycamptothecin Derivative (NMe)—The Chemotherapeutic Drug Candidate Versus Irinotecan (IR) on a Mouse Model”, Metabolites

A. Pareek, M. Morawiak, E. Masoumifeshani, P. Gaweł, „Photostable π-Expanded Furans via Base-Mediated Quinone Oxygen-Annulation”, J. Org. Chem.

M. Bugaj-Zarębska, J. Jaźwiński, „Theoretical investigations of α,β-unsaturated carboxylic acids and related compounds: Non-covalent interactions and through-space indirect spin-spin couplings as common structural features”, Comput. Theor. Chem.

V. Sharma, P. Bartos, M. Morawiak, P. Gaweł, „Acid-Mediated Dimerization of TIPS-Pentacene”, J. Org. Chem.

D. Boczar, W. Bocian, K. Małek, M. Milczarek, A. E. Laudy, K. Michalska, „Physicochemical Characterisation of Ceftobiprole and Investigation of the Biological Properties of Its Cyclodextrin-Based Delivery System”, Int. J. Mol. Sci.

K. M. Bąk, O. Kisiel, D. Mondal, M. M. Zimnicka, M. J. Chmielewski, „Anion transport across lipid bilayers by a hydrogen bonding homo[2]catenane”, Chem. Commun.

D. Boczar, W. Bocian, J. Sitkowski, K. Pioruńska, K. Michalska,  „Development of a Cyclodextrin-Based Drug Delivery System to Improve the Physicochemical Properties of Ceftobiprole as a Model Antibiotic”, Int. J. Mol. Sci.

K. Unrug-Bielawska, D. Earnshaw, M. Cybulska-Lubak, E. Kaniuga, Z. Sandowska-Markiewicz, M. Statkiewicz, I. Rumieńczyk, M. Dąbrowska, J. Kocik-Król, K. Klimkiewicz, M. Urbanowicz, B. Naumczuk, L. Kozerski, M. Krzykawski, M. Mikula, J. Ostrowski, „Therapeutic Responses to Two New SN-38 Derivatives in Colorectal Cancer Patient-Derived Xenografts and Respective 3D In Vitro Cultures”, Anticancer Research

K. Lejwoda, A. Gumieniczek, A. Filip, B. Naumczuk, „Two Small Molecule Drugs with Topical Applications, Diflunisal and Naphazoline, and Their Potentially Toxic Photodegradants: Analysis by Chemical and Biological Methods”, Molecules

J. Hetmańczyk, Ł. Hetmańczyk, J. Nowicka-Scheibe, A. Pawlukojć, J. K. Maurin, A. Budzianowski, W. Schilf, „Investigation of hydrogen bonds in proton transfer complexes derived from the reaction of 2- and 4-(N,N-dimethylamino)pyridines with chloranilic acid”, Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy

K. Lejwoda, A. Gumieniczek, A. Filip, B. Naumczuk, „The Study on Timolol and Its Potential Phototoxicity Using Chemical, In Silico and In Vitro Methods”, Pharmaceuticals

M. Rojkiewicz, P. Kuś, J. Kusz, M. Książek, D. Staszek, „Spectroscopic and Crystallographic Characterization of Two Hydrochloride Cathinones: 1-(4-fluoro-3-methylphenyl)-2-(pyrrolidin-1-yl)pentan-1-one (4-F-3-Me-α-PVP) and N-ethyl-2-amino-1-phenylheptan-1-one (N-ethylheptedrone)”, Crystals

M. E. Zimens, V. V. Ilyushenkova, M. D. Matveeva, D. I. Zhilyaev, D. S. Sosnin, N. V. Davidovskiy, R. S. Borisov, „Fragmentation of Doubly-Charged Negative Ions of Dicarboxylic Acids under Collision-Induced Dissociation Conditions”, J. Anal. Chem.

M. Gano, E. Janus, W. Schilf, „Chiral Pyrrolidinium Ionic Liquids with (−)-Borneol Fragment in the Cation – Synthesis, Physicochemical Properties and Application in Diels-Alder Reaction”, ChemPhysChem

A. Maranda, W. Schilf, M. Gucma, W. M. Gołębiewski, M. Krawczyk, W. Pucko, „Chemical synthesis of acetamiprid ammonium salts, spectroscopic studies on their isomeric equilibrium structures and their fungicidal activity”, Przemysł Chemiczny

N. Skrzypczak, K. Pyta, W. Bohusz, A. Leśniewska, M. Gdaniec, P. Ruszkowski, W. Schilf, F. Bartl, P. Przybylski, „Cascade Transformation of the Ansamycin Benzoquinone Core into Benzoxazole Influencing Anticancer Activity and Selectivity”, J. Org. Chem.

M. Matussek, A. Kurpanik-Wójcik, S. Gogoc, A. Fijołek, M. Filapek, B. Naumczuk, P. Data, „Electroactive Dyes Based on 1,8-Naphthalimide with Acetylene Linkers as Promising OLED Materials – the Relationship Between Structure and Photophysical Properties”, Chem. Eur. J.

M. Sowińska, M. Szeliga, M. Morawiak, B. Zabłocka, Z. Urbańczyk-Lipkowska, „Design, synthesis and activity of new N1-alkyl tryptophan functionalized dendrimeric peptides against glioblastoma”, Biomolecules

B. Kołodziej, B. Duran, M. Morawiak, W. Schilf, „Unusual products of reaction between aminoisoxazoles and aromatic aldehydes”, J. Mol. Struct.

M. Sowińska, M. Szeliga, M. Morawiak, E. Ziemińska, B. Zabłocka, Z. Urbanczyk-Lipkowska, „Peptide dendrimers with non-symmetric bola structure exert long term effect on glioblastoma and neuroblastoma cell lines”, Biomolecules

M. Cieślak, D. Ryszawy, M. Pudełek, M. Urbanowicz, M. Morawiak, O. Staszewska-Krajewska, J. Czyż, Z. Urbanczyk-Lipkowska, „Bioinspired bola-type peptide dendrimers inhibit proliferation and invasiveness of glioblastoma cells in a manner dependent on their structure and amphipathic properties”, Pharmaceutics

M. Pitucha, Z. Karczmarzyk, M. Swatko-Ossor, M. Drozd, W. Wysocki, G. Ginalska, Z. Urbańczyk-Lipkowska, D. Kowalczuk, M. Morawiak, „Synthesis and structural study of some N-acyl-4-allylsemicarbazides and the product of their cyclization with a potential antimicrobial activity”, J. Mol. Struct.

D. Branowska, Z. Karczmarzyk, E. Wolińska , W. Wysocki, M. Morawiak, Z. Urbańczyk-Lipkowska, A. Bielawska, K. Bielawski, „1,2,4-triazine sulfonamides: synthesis by sulfenamide intermediates, in vitro anticancer screening, structural characterization and molecular docking study”, Molecules

M. Morawiak, M. Stolarska, M. Cieślak, Z. Urbanczyk-Lipkowska,  „Interactions of rationally designed small peptide dendrons functionalised with valine or sinapic acid with α-helix and β-sheet structures of poly-L-lysine and poly-L-glutamic acid”, Peptide Science

M. Sowinska, M. Morawiak, M. Bochyńska-Czyż, A.W. Lipkowski, E. Ziemińska, B. Zabłocka, Z. Urbanczyk-Lipkowska, „Molecular antioxidant properties and in vitro cell toxicity of the p-aminobenzoic acid (PABA) functionalized peptide dendrimers”, Biomolecules

B. Kołodziej, M. Morawiak, W. Schilf, B. Kamieński, „Structure investigations of Schiff bases derived from 3-amino1H-1,2,4-triazole”, J. Mol. Struct.

K. Tanaka, T. Kawakita, M. Morawiak, Z. Urbanczyk-Lipkowska, „A novel homochiral metal–organic framework with expanded open cage based on (R)-3,3′-bis(6-carboxy-2-naphthyl)-2,2′-dihydroxy-1,1′-binaphthyl: Synthesis, X-ray structure and efficient HPLC enantiomer separation”, Cryst. Eng. Comm.