Head of the group
Prof. Sławomir Jarosz

Professors
Prof. IChO PAN Zbigniew Pakulski

Adjuncts
Dr Mykhaylo Potopnyk

Assistans
Dr Anna Osuch-Kwiatkowska

Chemists
Romuald Karczewski

PhD students
Mgr inż. Karolina Tiara

OPUS NCN – 2016/21/B/ST5/03382 „Synteza i właściwości kryptandów zawierających rdzeń sacharozy”

OPUS NCN – 2016/21/B/ST5/02141 „Modyfikacje pierścienia A betuliny w syntezie związków cytotoksycznych” (Kierownik: dr hab. inż. Zbigniew Pakulski).

Publications

Z. Pakulski, P. Cmoch, A. Korda, R. Luboradzki, K. Gwardiak, R. Karczewski, „Rearrangements of the Betulin Core. Synthesis of Terpenoids Possessing the Bicyclo[3.3.1]nonane Fragment by Rearrangement of Lupane-Type Epoxides”, J. Org. Chem.

Ł. Szyszka, P. Cmoch, M. Górecki, M. Ceborska, M. Potopnyk, S. Jarosz, „Chiral Molecular Cages Based on Cyclotriveratrylene and Sucrose Units Connected with p-Phenylene Linkers”, Eur. J. Org. Chem.

J. S. Sepioł, A. Ramanenka, R. Karczewski, A. Grabowska, „Searching for a near-infrared fluorescence band supporting a hypothetical double proton transfer in ESIPT reaction of 2,5-bis(2′-benzoxazolyl) hydroquinone (BBHQ), as requested by theoreticians”, J. Mol. Struct.

J. Jaźwiński, P. Łata, K. Tiara, S. Jarosz, „Striking difference in reactivity of trienes and oximes derived from glucose and xylose”, Arkivoc

Ł. Szyszka, M. Górecki, P. Cmoch, S. Jarosz, “Fluorescent Molecular Cages with Sucrose and Cyclotriveratrylene Units for the Selective Recognition of Choline and Acetylcholine”, J. Org. Chem.

P. Soko­łowska, K. Dąbrowa, S. Jarosz, “Visible-Light Responsive Sucrose-Containing Macrocyclic Host for Cations”, Org. Lett.

K. Kuczyńska, J. Jaźwiński, Z. Pakulski, P. Cmoch, R. Luboradzki, „Oxidative Functionalization of Trinor-18α-olean-17(22)-ene Derivatives. Annulation of the E-Ring by an Intramolecular Aldol Reaction”, J. Org. Chem.

M. A. Potopnyk, „1,3,5,2-Oxadiazaborinines as a class of fluorescent organoboron dyes”, Targets in Heterocyclic Systems

M. A. Potopnyk, M. Kravets, R. Luboradzki, D. Volyniuk, V. Sashuk, J. V. Grazulevicius, „Carbazole-modified thiazolo[3,2-c][1,3,5,2]oxadiazaborinines exhibiting aggregation-induced emission and mechanofluorochromism”, Org. Biomol. Chem. 

M. A. Potopnyk, D. Volyniuk, R. Luboradzki, A. Lazauskas, J. V. Grazulevicius, „Aggregation-Induced Emission-Active Carbazolyl-Modified Benzo[4,5]thiazolo[3,2-c]oxadiazaborinines as Mechanochromic Fluorescent Materials”, Eur. J. Org. Chem.

K. Kuczyńska, B. Bończak, L. Rárová, M. Kvasnicová, M. Strnad, Z. Pakulski, P. Cmoch, M. Fiałkowski, „Synthesis and cytotoxic activity of 1,2,3-triazoles derived from 2,3-seco-dihydrobetulin via a click chemistry approach”, J. Mol. Struct.

G. Witkowski, M. Potopnyk, K. Tiara, A. Osuch-Kwiatkowska, S. Jarosz, „Synthesis of Highly Oxygenated Bicyclic Carbasugars. Remarkable Difference in the Reactivity of the d-gluco and d-xylo- Derived Trienes”, Molecules

Z. Pakulski, P. Cmoch, A. Korda, R. Luboradzki, K. Gwardiak, R. Karczewski, „Rearrangements of the Betulin Core. Synthesis of Terpenoids Possessing the Bicyclo[3.3.1]nonane Fragment by Rearrangement of Lupane-Type Epoxides”, J. Org. Chem.

S. Jarosz, P. Sokołowska, Ł. Szyszka, „Synthesis of fine chemicals with high added value from sucrose: Towards sucrose-based macrocycles”, Tetrahedron Letters

M. A. Potopnyk, D. Volyniuk, R. Luboradzki, M. Ceborska, I. Hladka, Y. Danyliv, J. V. Grazulevicius, „Organolithium-Mediated Postfunctionalization of Thiazolo[3,2- c][1,3,5,2]oxadiazaborinine Fluorescent Dyes”, J. Org. Chem.

A. Korda, L. Rárová, Z. Pakulski, M. Strnad, J. Oklešťková, K. Kuczynska, P. Cmoch, K. Gwardiak, R. Karczewski, „New lupane bidesmosides exhibiting strong cytotoxic activities in vitro”, Bioorganic Chemistry

K. Tiara, M. Potopnyk, P. Świder, S. Jarosz, „Stereocontrolled Debenzylative Cycloetherification Reaction as a Route to Enantiopure C-Furanosides with Amino Substituents in the Side Chain”, J. Org. Chem.

Ł. Szyszka, P. Cmoch, A. Butkiewicz, M. Potopnyk, S. Jarosz, „Synthesis of Cyclotriveratrylene-Sucrose-Based Capsules”, Org. Lett.

A. Gajewska, A. Osuch-Kwiatkowska, S. Jarosz, „Synthesis of sulfur containing macrocycles with sucrose scaffold”, Carbohydr. Res.

P. Sokołowska, M. Kowalski, S. Jarosz, „First Synthesis of Cryptands with Sucrose Scaffold, Beilstein”, J. Org. Chem.

S. Jarosz, K. Tiara, M. A. Potopnyk, „Stereoselective synthesis of sugar mimetics from simple monosaccharides”, Pur. Appl. Chem.

M. A. Potopnyk, D. Volyniuk, R. Luboradzki, M. Ceborska, I. Hladka, Y. Danyliv, J. V. Grazulevicius, „Application of the Suzuki-Miyaura Reaction for the Postfunctionalization of the Benzo[4,5]thiazolo[3,2-c][1,3,5,2]oxadiazaborinine Core: An Approach towards Fluorescent Dyes”, J. Org. Chem.

K. Tiara, M. A. Potopnyk, S. Jarosz, „Synthesis of sucrose-based macrocycle with unsymmetrical monosaccharides „arms” ” , Beilstein J. Org. Chem.

K. Łęczycka-Wilk, F. Ulatowski, P. Cmoch, S. Jarosz, „ „Choose-a-Size” Control in the Synthesis of Sucrose Based Thiourea Macrocycles”, Org. Biomol. Chem.

B. Chaciak, K. Dąbrowa, P. Świder, S. Jarosz, „Macrocyclic Derivatives with Sucrose Scaffold: Insertion of a Long Polyhydroxylated Linker Between the Terminal 6,6’-Positions”, New J. Chem.

A. Korda, Z. Pakulski, P. Cmoch, K. Gwardiak, R. Karczewski, „Synthesis of bidesmosidic lupane saponins – comparison of batch and continuous-flow methodologies”, Carbohydr. Res.

M. A. Potopnyk, R. Lytvyn, Y. Danyliv, M. Ceborska, O. Bezvikonnyi, D. Volyniuk, J. V. Gražulevičius, „N,O π-Conjugated 4-Substituted 1,3-Thiazole BF2 Complexes: Synthesis and Photophysical Properties”, J. Org. Chem.

M. A. Potopnyk, D. Volyniuk, M. Ceborska, P. Cmoch, I. Hladka, Y. Danyliv, J. V. Gražulevičius, „Benzo[4,5]thiazolo[3,2-c][1,3,5,2]oxadiazaborinines: Synthesis, Structural, and Photophysical Properties”, J. Org. Chem.

M. Szewczyk, M. Morawiak, A. Narczyk, Z. Pakulski, Z. Urbańczyk-Lipkowska, „Chlorogenic acids mimics – synthesis, structure and antioxidant activity”, J. Chem. Biochem.

M.A. Potopnyk, B. Lewandowski, S. Jarosz, „Novel sucrose-based macrocyclic receptors for enantioselective recognition of chiral ammonium cations”, Tetrahedron: Asymmetry

M.A. Potopnyk, P. Cmoch, S. Jarosz, „Short Synthesis of Diamide-Linked Sucrose Macrocycles”, Org. Lett.

Documents

Research topics

  • Chemistry of sucrose. Towards sucrose-based macrocyclic receptors
  • Stereocontrolled organic synthesis directed to sugar mimetics
  • Synthesis of biologically active oligosaccharides, triterpenes, and saponins
  • Highly luminescent organoboron complexes