Head of the group
Prof. IChO PAN Wojciech Chaładaj

PhD Students
Mgr Aleksandra Błocka
Mgr Bartosz Bisek
Mgr Prachi Shah
Mgr Shrenik Seth

NCN SONATA BIS 2016/22/E/ST5/00537
Tandem palladium-catalyzed additions of enolates to alkynes followed by coupling with (hetero) aryl halides”

NCN OPUS 2019/35/B/ST4/00599
Control of regio- and stereoselectivity of hydro- and carbofluoromethylation of alkynes via a sequence of hydro- or carbometallation and C-M functionalization”

Publications

W. Chaładaj, A. Kołodziejczyk, S. Domański, „Gold(I)-Catalyzed Conia-ene Cyclization of Internal ϵ-Acetylenic β-Ketoesters under High Pressure.”, ChemCatChem

S. Domański, O. Staszewska-Krajewska, W. Chaładaj, Pd-Catalyzed Carbonylative Carboperfluoroalkylation of Alkynes. „Through-Space 13C–19F Coupling as a Probe for Configuration Assignment of Fluoroalkyl-Substituted Olefins.”, J. Org. Chem.

M. Białkowska, W. Chaładaj, I. Deperasińska, A. Drzewiecka-Antonik, A. E. Koziol, A. Makarewicz, B. Kozankiewicz, „Single molecules of terrylene in di-substituted naphthalenes crystallizing in the herringbone pattern.”, RSC Adv.

Research topics

  • Discovery of new Pd-catalyzed multicomponent transformations of alkynes enabling efficient direct assembly of simple building blocks into an elaborate target molecule.
  • Development of methods for fluoroalkylation of organic compounds, especially through tandem or sequential catalysis
  • Development of tandem reactions involving additions to alkynes and subsequent functionalization via cross-coupling
  • Investigation of the mechanisms of transition metal-catalyzed reactions