Group XII.
Organic Crystallochemistry

Staff:

Beata Przykorska M.Sc., Piotr Polcyn, Ph.D. student.

Research activity

X-Ray structure determination and analysis is a main tool in our research. The principal area of research involves studies of the solid state structure of organic compounds in relation to their biological, physical and chemical properties. Current research covers:

·         structure-activity studies of small bioactive peptide dendrimers

·         mechanism and stereoselectivity of solid-state inclusion processes (in cooperation with Prof. F. Toda of Okayama University, Japan)

·         crystal engineering for application in non-solvent  processes

Laboratory is equipped with automated four-circle diffractometer MACH3 with opportunity of data collection in the temperature range from 100 K to ambient. Laboratory provides custom measurements and/or expertise assistance in crystal structure determination for and outside of the Institute.

Selected scientific publications:

1.         B. Szczesna and Z. Urbańczyk - Lipkowska: CrystEngComm., 5, 385 (2003), “Engineering anthracene-based binary systems dedicated for reactions in non-solvent conditions”.

2.         K. Tanaka, T.Z. Hiratsuka and Z. Urbańczyk- Lipkowska: Eur. J. Org. Chem., 16, 3043 (2003), “Novel chiral amide hosts derived from mandelic acid: A marked difference in inclusion abilities between host stereoisomers”.

3.         J. Janiszewska, J. Swieton, A.W. Lipkowski and Z. Urbańczyk-Lipkowska:, Bioorg. Med. Chem. Lett 13, 3711(2003), “Low molecular mass peptide dendrimers that express antimicrobial properties”

4.         Z. Urbańczyk-Lipkowska and J. Janiszewska:., Polimery 48, 54 (2003), “Organometallic dendrimers - molecular architecture and functions”.