Group
I.
Mass Spectrometry
Head of the groupProf. Witold Danikiewicz
e-mail: witold@icho.edu.pl |
1984 - Ph.D., Department of Chemistry, Warsaw University of Technology. 1987-1988 - Post-doc, Indiana University, Bloomington, USA. 1999 - Habilitation, Institute of Organic Chemistry PAS. 2005 - Full professor, Institute of Organic Chemistry, PAS. |
Staff:
Tomasz Bieńkowski, Ph.D.; Małgorzata Grela, M.Sc.; Małgorzata Kania, M.Sc.; Barbara Kawczyńska, techn.; Marian Olejnik, M.Sc.; Małgorzata Świst, M.Sc.; Magdalena Zimnicka, Ph.D. student
Research activity
Research
activities of the Mass Spectrometry Group concentrate on the gas-phase
chemistry of the phenide anions and anionic sigma-adducts.
We have developed a method for the in-source generation of the substituted
phenide anions from the appropriate benzoic acids using an electrospray
ion source. The reactions of these anions in the ion source and in the
collision cell can be studied using a triple quadrupole mass spectrometer.
An important example are the reactions of di- and trinitrophenide anions
with selected C-H acids resulting in the formation of anionic sigma-adducts, which opens a way to study these species in a gas phase.
We are also continuing our research on the fragmentation reactions mechanisms upon electron ionization, especially ion-neutral complexes and elimination of the small neutrals. Particular attention is directed to the EI-induced reactions of N-alkoxymethyl derivatives of the secondary amides, sulphonamides and phosphamides including lactams and sultams.
Selected scientific publications:
1. „Complexes of Bivalent Metal Cations in Electrospray Mass Spectra of Common Organic Compounds” T. Bieńkowski, A. Brodzik-Bieńkowska, W. Danikiewicz, J. Mass Spectrom., 37, 617 (2002).
2. „Electron Ionization-Induced Fragmentation of N-alkoxymethylanilides” W. Danikiewicz, R. Szmigielski, M. Olejnik, J. Mass Spectrom., 38, 58 (2003).
3. „N-Alkoxymethylation of Secondary Amides, Sulfonamides and Phosphamides Using Dialkoxymethanes in the Presence of the Lewis Acids” R. Szmigielski, W. Danikiewicz, Synlett, 2003, 372.
4. „Generation and Reactions of Substituted Phenide Anions in an Electrospray – Triple Quadrupole Mass Spectrometer”, T. Bieńkowski, W. Danikiewicz, Rapid Commun. Mass Spectrom., 17, 697 (2003).
5. „Application of Electrospray Ionization Mass Spectrometry for Studies of Anionic s‑Adducts of Aromatic Nitrocompounds”, W. Danikiewicz, T. Bieńkowski, K. Wojciechowski, Tetrahedron Lett., 45, 931 (2004).
